Different neuroplastic processes can occur along the nociceptive pathways and may be
important in the transition from acute to chronic pain and for diagnosis and development of …

There is tremendous interpatient variability in the response to analgesic therapy (even for
efficacious treatments), which can be the source of great frustration in clinical practice. This …

Quantitative sensory testing (QST) is a psychophysical method used to quantify
somatosensory function in response to controlled stimuli in healthy subjects and patients …

Pain is the dominant symptom in osteoarthritis (OA) and sensitization may contribute to the
pain severity. This study investigated the role of sensitization in patients with painful knee …

Hypersensitivity due to central pain mechanisms can influence recovery and lead to worse
clinical outcomes, but the ability of quantitative sensory testing (QST), an index of …

Studies have suggested that quantitative sensory testing (QST) might hold a predictive value
for the development of chronic postoperative pain and the response to pharmacological …

OBJECTIVE: To systematically review the use of Quantitative sensory testing (QST) in pain
characterisation (phenotyping) in Osteoarthritis (OA). METHODS: Six bibliographic …

The aim of this Review is to give a short presentation of the manifestations, assessment
methods, and mechanisms underlying localized and widespread musculoskeletal pain …

Central sensitization (CS), simply defined as an amplified response of the central nervous
system to peripheral input, is a concept of great importance in clinical medicine. It has …

Objective The modest association between radiographic joint damage and pain in
osteoarthritis (OA) has led to the suggestion of facilitated central pain processing. This study …