Stress and the dopaminergic reward system
JH Baik - Experimental & molecular medicine, 2020 - nature.com
Dopamine regulates reward-related behavior through the mesolimbic dopaminergic
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …
pathway. Stress affects dopamine levels and dopaminergic neuronal activity in the …
Toward a better understanding of the mechanisms and pathophysiology of anhedonia: are we ready for translation?
DA Pizzagalli - American Journal of Psychiatry, 2022 - Am Psychiatric Assoc
Anhedonia—the loss of pleasure or lack of reactivity to pleasurable stimuli—remains a
formidable treatment challenge across neuropsychiatric disorders. In major depressive …
formidable treatment challenge across neuropsychiatric disorders. In major depressive …
Behavioural and dopaminergic signatures of resilience
Chronic stress can have lasting adverse consequences in some individuals, yet others are
resilient to the same stressor,. Susceptible and resilient individuals exhibit differences in the …
resilient to the same stressor,. Susceptible and resilient individuals exhibit differences in the …
The brain reward circuitry in mood disorders
SJ Russo, EJ Nestler - Nature reviews neuroscience, 2013 - nature.com
Mood disorders are common and debilitating conditions characterized in part by profound
deficits in reward-related behavioural domains. A recent literature has identified important …
deficits in reward-related behavioural domains. A recent literature has identified important …
Stress and the social brain: behavioural effects and neurobiological mechanisms
Stress often affects our social lives. When undergoing high-level or persistent stress,
individuals frequently retract from social interactions and become irritable and hostile …
individuals frequently retract from social interactions and become irritable and hostile …
[HTML][HTML] Stress-induced plasticity and functioning of ventral tegmental dopamine neurons
EH Douma, ER de Kloet - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional,
motivational, and social reward associations together with their more demanding cognitive …
motivational, and social reward associations together with their more demanding cognitive …
Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons
Ventral tegmental area (VTA) dopamine neurons in the brain's reward circuit have a crucial
role in mediating stress responses,,,, including determining susceptibility versus resilience to …
role in mediating stress responses,,,, including determining susceptibility versus resilience to …
Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression
Enhanced glutamatergic transmission in the nucleus accumbens (NAc), a region critical for
reward and motivation, has been implicated in the pathophysiology of depression; however …
reward and motivation, has been implicated in the pathophysiology of depression; however …
Neurobiology of resilience: interface between mind and body
Stress-related neuropsychiatric disorders, such as major depressive disorder and
posttraumatic stress disorder, exact enormous socioeconomic and individual consequences …
posttraumatic stress disorder, exact enormous socioeconomic and individual consequences …
Dopamine neurons modulate neural encoding and expression of depression-related behaviour
Major depression is characterized by diverse debilitating symptoms that include
hopelessness and anhedonia. Dopamine neurons involved in reward and motivation …
hopelessness and anhedonia. Dopamine neurons involved in reward and motivation …