In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

As the most frequent and vulnerable malignancy among women, breast cancer universally
manifests a formidable healthcare challenge. From a biological and molecular perspective, it …

Colorectal carcinoma (CRC) is the third most common cancer in terms of diagnosis and the
second in terms of mortality. Recent studies have shown that various proteins, extracellular …

In recent years, liquid biopsy has emerged as an alternative method to diagnose and
monitor tumors. Compared to classical tissue biopsy procedures, liquid biopsy facilitates the …

Purpose: Detection of colorectal carcinomas at a time when there are more treatment
options is associated with better outcomes. This prospective case–control study assessed …

Cancer has a high incidence and lethality rate, which is a significant threat to human health.
With the development of high-throughput technologies, different types of cancer genomics …

Gastrointestinal (GI) cancers account for one-fourth of the global cancer incidence and are
incriminated to cause one-third of cancer-related deaths. GI cancer includes esophageal …

The fragmentation patterns of cell-free DNA (cfDNA) in plasma can potentially be utilized as
diagnostic biomarkers in liquid biopsy. However, our knowledge of this biological process …

Epigenetic mechanisms govern the transcriptional activity of lineage-specifying enhancers;
but recent work challenges the dogma that joint chromatin accessibility and DNA …

Plasma cell-free DNA (cfDNA) fragmentation patterns are emerging directions in cancer
liquid biopsy with high translational significance. Conventionally, the cfDNA sequencing …