Signaling pathway of MAPK/ERK in cell proliferation, differentiation, migration, senescence and apoptosis

Y Sun, WZ Liu, T Liu, X Feng, N Yang… - Journal of Receptors …, 2015 - Taylor & Francis
The generic mitogen-activated protein kinases (MAPK) signaling pathway is shared by four
distinct cascades, including the extracellular signal-related kinases (ERK1/2), Jun amino …

Dietary polyphenols in prevention and treatment of prostate cancer

RK Lall, DN Syed, VM Adhami, MI Khan… - International journal of …, 2015 - mdpi.com
Prostate cancer is the most prevalent disease affecting males in many Western countries,
with an estimated 29,480 deaths in 2014 in the US alone. Incidence rates for prostate cancer …

Pterostilbene: Mechanisms of its action as oncostatic agent in cell models and in vivo studies

Z Ma, X Zhang, L Xu, D Liu, S Di, W Li, J Zhang… - Pharmacological …, 2019 - Elsevier
Pterostilbene, a natural dimethylated analog of resveratrol, exerts pleiotropic anticancer
effects against a variety of cancer types. Due to the better lipophilic and oral absorption …

Targeted bioimaging and sensing of folate receptor-positive cancer cells using folic acid-conjugated sulfur-doped graphene quantum dots

S Kadian, G Manik, N Das, P Roy - Microchimica Acta, 2020 - Springer
For the first time is reported a facile in situ synthesis of folic acid-conjugated sulfur-doped
graphene quantum dots (FA-SGQDs) through simple pyrolysis of citric acid (CA), 3 …

Pterostilbene suppresses ovarian cancer growth via induction of apoptosis and blockade of cell cycle progression involving inhibition of the STAT3 pathway

W Wen, G Lowe, CM Roberts, J Finlay, ES Han… - International Journal of …, 2018 - mdpi.com
A growing body of evidence has demonstrated the promising anti-tumor effects of resveratrol
in ovarian cancer cells, including its inhibitory effects on STAT3 activation. Nonetheless, the …

Apoptotic and nonapoptotic activities of pterostilbene against cancer

RJ Chen, HC Kuo, LH Cheng, YH Lee… - International journal of …, 2018 - mdpi.com
Cancer is a major cause of death. The outcomes of current therapeutic strategies against
cancer often ironically lead to even increased mortality due to the subsequent drug …

Inflammation in Prostate Cancer: Exploring the Promising Role of Phenolic Compounds as an Innovative Therapeutic Approach

R Fernandes, C Costa, R Fernandes, AN Barros - Biomedicines, 2023 - mdpi.com
Prostate cancer (PCa) remains a significant global health concern, being a major cause of
cancer morbidity and mortality worldwide. Furthermore, profound understanding of the …

KCNN4 promotes invasion and metastasis through the MAPK/ERK pathway in hepatocellular carcinoma

QT Li, YM Feng, ZH Ke, MJ Qiu, XX He… - Journal of …, 2020 - journals.sagepub.com
Hepatocellular Carcinoma (HCC) is one of the most common malignancies in the world, and
is well-known for its bad prognosis. Potassium calcium-activated channel subfamily N …

Pterostilbene modulates the suppression of multidrug resistance protein 1 and triggers autophagic and apoptotic mechanisms in cisplatin-resistant human oral cancer …

HP Chang, CC Lu, JH Chiang… - International …, 2018 - spandidos-publications.com
Pterostilbene is a natural polyphenolic compound that is primarily found in fruits, such as
blueberries and has a similar structure to resveratrol. Pterostilbene exhibits antioxidant, anti …

Metastasis-associated protein 1-mediated antitumor and anticancer activity of dietary stilbenes for prostate cancer chemoprevention and therapy

AS Levenson - Seminars in cancer biology, 2022 - Elsevier
Dietary bioactive polyphenols that demonstrate beneficial biological functions including
antioxidant, anti-inflammatory, and anticancer activity hold immense promise as effective …