Cell death occurs in all domains of life. While some cells die in an uncontrolled way due to
exposure to external cues, other cells die in a regulated manner as part of a genetically …

Death is an important part of an organism's existence and also marks the end of life. On a
cellular level, death involves the execution of complex processes, which can be classified …

Abstract Calcium (Ca2+) influx into mitochondria occurs through a Ca2+-selective uniporter
channel, which regulates essential cellular processes in eukaryotic organisms. Previous …

The mitochondrial calcium uniporter is a highly selective ion channel composed of species-
and tissue-specific subunits. However, the functional role of each component still remains …

Chitosan is a natural polymer with antimicrobial activity. Chitosan causes plasma membrane
permeabilization and induction of intracellular reactive oxygen species (ROS) in Neurospora …

Fusarium oxysporum is an important plant pathogen and an emerging opportunistic human
pathogen. Germination of conidial spores and their fusion via conidial anastomosis tubes …

Introduction: The widespread implementation of immunosuppressants, immunomodulators,
hematopoietic stem cell transplantation and solid organ transplantation in clinical practice …

Abstract PMAP-23 (RIIDLLWRVRRPQKPKFVTVWVR-NH2) is an antimicrobial peptide
(AMP) derived from porcine myeloid. Membrane disruption is thought to underpin the …

Our interest in the mitochondria of Candida albicans has progressed to the identification of
several proteins that are critical to complex I (CI) activity. We speculated that there should be …

The mitochondrial calcium uniporter (MCU) is a calcium-activated calcium channel critical
for signaling and bioenergetics. MCU, the pore-forming subunit of the uniporter, contains two …