The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2
L Bauer, BM Laksono, FMS de Vrij, SA Kushner… - Trends in …, 2022 - cell.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is associated with
a diverse spectrum of neurological complications during the acute and postacute stages …
a diverse spectrum of neurological complications during the acute and postacute stages …
[HTML][HTML] Human organoid models to study SARS-CoV-2 infection
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
syndrome coronavirus 2 (SARS-CoV-2) is one of the deadliest pandemics in history. SARS …
Design of SARS-CoV-2 PLpro inhibitors for COVID-19 antiviral therapy leveraging binding cooperativity
Antiviral agents that complement vaccination are urgently needed to end the COVID-19
pandemic. The SARS-CoV-2 papain-like protease (PLpro), one of only two essential …
pandemic. The SARS-CoV-2 papain-like protease (PLpro), one of only two essential …
Morphological, cellular, and molecular basis of brain infection in COVID-19 patients
Although increasing evidence confirms neuropsychiatric manifestations associated mainly
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …
[HTML][HTML] Characterization and biomarker analyses of post-COVID-19 complications and neurological manifestations
As the SARS-CoV-2 pandemic continues, reports have demonstrated neurologic sequelae
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …
following COVID-19 recovery. Mechanisms to explain long-term neurological sequelae are …
[HTML][HTML] Cerebral dysfunctions caused by sepsis during ageing
T Manabe, MT Heneka - Nature Reviews Immunology, 2022 - nature.com
Systemic inflammation elicited by sepsis can induce an acute cerebral dysfunction known as
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
sepsis-associated encephalopathy (SAE). Recent evidence suggests that SAE is common …
Neuropilin-1 mediates SARS-CoV-2 infection of astrocytes in brain organoids, inducing inflammation leading to dysfunction and death of neurons
ABSTRACT Coronavirus disease 2019 (COVID-19) is frequently associated with
neurological deficits, but how severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
neurological deficits, but how severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
Neuropsychiatric aspects of long COVID: a comprehensive review
Although some patients have persistent symptoms or develop new symptoms following
coronavirus disease 2019 (COVID‐19) infection, neuropsychiatric aspects of long COVID …
coronavirus disease 2019 (COVID‐19) infection, neuropsychiatric aspects of long COVID …
[HTML][HTML] Network medicine links SARS-CoV-2/COVID-19 infection to brain microvascular injury and neuroinflammation in dementia-like cognitive impairment
Background Dementia-like cognitive impairment is an increasingly reported complication of
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …
SARS-CoV-2 infection. However, the underlying mechanisms responsible for this …
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis
Pseudouridine is the most frequent epitranscriptomic modification. However, its cellular
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …
functions remain largely unknown. Here, we show that pseudouridine synthase 7 (PUS7) is …