Critical-sized bone defects and articular cartilage injuries resulting from trauma,
osteonecrosis, or age-related degeneration can be often non-healed by physiological …

Implantation is a modern method of administering chemotherapeutic agents, with a highly
targeted effect and better patient tolerance due to the low frequency of administration …

Chitosan is quite a unique polysaccharide due to the presence of the amine groups naturally
occurring in its structure. This feature renders it into a polycation which makes it appealing …

Gelatin-based hydrogels have emerged as a popular scaffold material for tissue engineering
applications. The introduction of variable crosslinking methods has shown promise for …

Here, super-macroporous cryogel from a natural polysaccharide, pullulan was synthesized
using a cryo-crosslinking technique with divinyl sulfone (DVS) as a crosslinker. The …

Focal cartilage defects are a prevalent knee problem affecting people of all ages. Articular
cartilage (AC) possesses limited healing potential, and osteochondral defects can lead to …

Articular cartilage degeneration poses a significant public health challenge; techniques such
as 3D bioprinting are being explored for its regeneration in vitro. Gelatin-based hydrogels …

To address the issue of limited bone repair efficacy, a novel biomimetic HA/GT-OSA
composite was synthesized through crosslinking gelatin (GT) with oxidized sodium alginate …

Focal cartilage defects are a prevalent knee problem affecting people of all ages. Due to its
avascular nature, cartilage has limited self-repair capacity, and osteochondral defects can …

Critical sized bone defects and articular cartilage injuries resulting from trauma,
osteonecrosis or age-related degeneration are often nonhealing by the physiological …