Background The number of healthcare interventions described as 'personalised
medicine'(PM) is increasing rapidly. As healthcare systems struggle to decide whether to …

Pharmacogenomics (PGx) studies the use of genetic data to optimize drug therapy.
Numerous clinical centers have commenced implementing pharmacogenetic tests in clinical …

Substantial inter-individual discrepancies exist in both therapeutic effectiveness and
adverse effects of antidepressant and antipsychotic medications, which can, in part, be …

Pharmacogenetic (PGx) literature has shown beneficial outcomes in safety, efficacy and cost
when evidence-based gene-drug decision making is incorporated into clinical practice. PGx …

Current best practices in tumor registries provide a glimpse into a limited time frame over the
natural history of disease, usually a narrow window around diagnosis and biopsy. This …

Purpose We describe the implementation of CYP2D6-focused pharmacogenetic testing to
guide opioid prescribing in a quaternary care, nonprofit pediatric academic medical center …

Many anticancer drugs cause adverse drug reactions (ADRs) that negatively impact safety
and reduce quality of life. The typical narrow therapeutic range and exposure-response …

Secondary findings (SFs) identified through genomic sequencing (GS) can offer a wide
range of health benefits to patients. Resource and capacity constraints pose a challenge to …

Objective To assess perspectives on pharmacogenetic (PGx) testing among members of the
American Association of Geriatric Psychiatry (AAGP). Design Cross-sectional survey …

Background Pharmacogenomics is an emerging and affordable tool that may improve
postoperative pain control. One challenge to successful pain control is the large …