Biosensor-guided discovery and engineering of metabolic enzymes

HG Hwang, DY Ye, GY Jung - Biotechnology Advances, 2023 - Elsevier
A variety of chemicals have been produced through metabolic engineering approaches, and
enhancing biosynthesis performance can be achieved by using enzymes with high catalytic …

Biocatalytic gateway to convert glycerol into 3-hydroxypropionic acid in waste-based biorefineries: Fundamentals, limitations, and potential research strategies

HM Zabed, S Akter, PF Rupani, J Akor, Y Zhang… - Biotechnology …, 2023 - Elsevier
Microbial conversion of bioenergy-derived waste glycerol into value-added chemicals has
emerged as an important bioprocessing technology due to its eco-friendliness, feasible …

Recent Progress in Metabolic Engineering of Escherichia coli for the Production of Various C4 and C5-Dicarboxylic Acids

D Ye, JH Moon, GY Jung - Journal of Agricultural and Food …, 2023 - ACS Publications
As an alternative to petrochemical synthesis, well-established industrial microbes, such as
Escherichia coli, are employed to produce a wide range of chemicals, including dicarboxylic …

Recent advances in metabolic engineering of microorganisms for the production of monomeric C3 and C4 chemical compounds

S Zhou, Y Zhang, Z Wei, S Park - Bioresource Technology, 2023 - Elsevier
Bio-based C3 and C4 bi-functional chemicals are useful monomers in biopolymer
production. This review describes recent progresses in the biosynthesis of four such …

Riboswitch-guided chalcone synthase engineering and metabolic flux optimization for enhanced production of flavonoids

HG Hwang, A Milito, JS Yang, S Jang, GY Jung - Metabolic Engineering, 2023 - Elsevier
Flavonoids are a group of secondary metabolites from plants that have received attention as
high value-added pharmacological substances. Recently, a robust and efficient bioprocess …

Biosensor-Assisted Engineering for Diverse Microbial Cellular Physiologies

JH Moon, S Nam, K Jeung, MH Noh… - Journal of Agricultural …, 2024 - ACS Publications
Recent advancements in biosensor technology have revolutionized the field of microbial
engineering, enabling efficient and precise optimization of strains for the production of …

In vitro enzymatic production of 3-hydroxypropionic acid from glycerol via CoA-independent pathway

H Jo, B Gu, M Jeon, SI Lim - Process Biochemistry, 2024 - Elsevier
Hydroxypropionic acid (3-HP) is a C3-based versatile platform chemical offering significant
industrial and environmental advantages over petrochemical derivatives. Microbial cell …