Host combats IBDV infection at both protein and RNA levels

S Zhang, S Zheng - Viruses, 2022 - mdpi.com
Infectious bursal disease (IBD) is an acute, highly contagious, and immunosuppressive
avian disease caused by infectious bursal disease virus (IBDV). In recent years, with the …

Infectious bursal disease virus' interferences with host immune cells: what do we know?

J Trapp, S Rautenschlein - Avian Pathology, 2022 - Taylor & Francis
Infectious bursal disease virus (IBDV) induces one of the most important
immunosuppressive diseases in chickens leading to high economic losses due to increased …

[HTML][HTML] Comparative RNA-Seq analysis reveals insights in Salmonella disease resistance of chicken; and database development as resource for gene expression in …

MA Dar, SM Ahmad, BA Bhat, TA Dar, Z ul Haq… - Genomics, 2022 - Elsevier
Salmonella, one of the major infectious diseases in poultry, causes considerable economic
losses in terms of mortality and morbidity, especially in countries that lack effective …

Identification of key transcription factors and their functional role involved in Salmonella typhimurium infection in chicken using integrated transcriptome analysis and …

SM Ahmad, SS Bhat, S Shafi, MA Dar, A Saleem, Z Haq… - BMC genomics, 2023 - Springer
Salmonella enterica serovar typhimurium is the cause of significant morbidity and mortality
worldwide that causes economic losses to poultry and is able to cause infection in humans …

Evaluating the breadth of neutralizing antibody responses elicited by infectious bursal disease virus genogroup A1 strains using a novel chicken B-cell rescue system …

VRAP Reddy, S Nazki, AJ Brodrick, A Asfor… - Journal of …, 2022 - Am Soc Microbiol
Eight infectious bursal disease virus (IBDV) genogroups have been identified based on the
sequence of the capsid hypervariable region (HVR)(A1 to A8). Given reported vaccine …

The complete protections induced by the oil emulsion vaccines of the novel variant infectious bursal disease viruses against the homologous challenges indicating the …

W Wang, Y Huang, Y Zhang, Y Qiao, J Shi… - Frontiers in Veterinary …, 2024 - frontiersin.org
Novel variant infectious bursal disease virus (nvIBDV) is an emerging genotype (A2dB1b)
that can cause severe and prolonged immunosuppression in young chickens. Despite …

Transcriptomic analysis of inbred chicken lines reveals infectious bursal disease severity is associated with greater bursal inflammation in vivo and more rapid …

AS Asfor, S Nazki, VRAP Reddy, E Campbell… - Viruses, 2021 - mdpi.com
In order to better understand differences in the outcome of infectious bursal disease virus
(IBDV) infection, we inoculated a very virulent (vv) strain into White Leghorn chickens of …

CD4+TGFβ+ cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity …

S Nazki, VRAP Reddy, N Kamble, JR Sadeyen… - Frontiers in …, 2023 - frontiersin.org
Introduction Infectious Bursal Disease Virus (IBDV) causes immunosuppression in chickens.
While B-cell destruction is the main cause of humoral immunosuppression, bursal T cells …

An improved, dual-direction, promoter-driven, reverse genetics system for the infectious bursal disease virus (IBDV)

X Hu, Z Chen, X Wu, Z Ding, Q Zeng, H Wu - Viruses, 2022 - mdpi.com
The infectious bursal disease virus (IBDV), one member of the Birnaviridae family, causes
immunosuppression in young chickens by damaging the mature B cells of the bursa of …

Generation of a novel attenuated IBDV vaccine strain by mutation of critical amino acids in IBDV VP5

H Gao, S Zhang, H Chang, Y Guo, Z Li, Y Wang, L Gao… - Vaccine, 2024 - Elsevier
Infectious bursal disease virus (IBDV) is an acute and highly infectious RNA virus known for
its immunosuppressive capabilities, chiefly inflicting rapid damage to the bursa of Fabricius …