Fertilization mechanisms in flowering plants

T Dresselhaus, S Sprunck, GM Wessel - Current Biology, 2016 - cell.com
Compared with the animal kingdom, fertilization is particularly complex in flowering plants
(angiosperms). Sperm cells of angiosperms have lost their motility and require transportation …

TRPM8 channels: Advances in structural studies and pharmacological modulation

C Izquierdo, M Martín-Martínez… - International Journal of …, 2021 - mdpi.com
The transient receptor potential melastatin subtype 8 (TRPM8) is a cold sensor in humans,
activated by low temperatures (> 10,< 28° C), but also a polymodal ion channel, stimulated …

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring

AK Short, KA Fennell, VM Perreau, A Fox… - Translational …, 2016 - nature.com
Recent studies have suggested that physiological and behavioral traits may be
transgenerationally inherited through the paternal lineage, possibly via non-genomic signals …

Paternal immune activation by poly I: C modulates sperm noncoding RNA profiles and causes transgenerational changes in offspring behavior

EA Kleeman, SN Reisinger, P Adithya… - Brain, Behavior, and …, 2024 - Elsevier
Paternal pre-conceptual environmental experiences, such as stress and diet, can affect
offspring brain and behavioral phenotypes via epigenetic modifications in sperm …

HENMT1 and piRNA stability are required for adult male germ cell transposon repression and to define the spermatogenic program in the mouse

SL Lim, ZP Qu, RD Kortschak, DM Lawrence… - PLoS …, 2015 - journals.plos.org
piRNAs are critical for transposable element (TE) repression and germ cell survival during
the early phases of spermatogenesis, however, their role in adult germ cells and the relative …

The impact of epididymal proteins on sperm function

I Björkgren, P Sipilä - Reproduction, 2019 - rep.bioscientifica.com
The epididymis is necessary for post-testicular sperm maturation as it provides the milieu
required for spermatozoa to gain the ability for progressive movement and fertilization. In the …

CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization

JI Ernesto, M Weigel Muñoz, MA Battistone… - Journal of Cell …, 2015 - rupress.org
Ca2+-dependent mechanisms are critical for successful completion of fertilization. Here, we
demonstrate that CRISP1, a sperm protein involved in mammalian fertilization, is also …

Trpm8

L Almaraz, JA Manenschijn, E de la Peña… - … Receptor Potential (TRP) …, 2014 - Springer
Transient receptor potential melastatin 8 (TRPM8) was originally cloned from prostate tissue.
Shortly thereafter, the protein was identified as a cold-and menthol-activated ion channel in …

An essential role for katanin p80 and microtubule severing in male gamete production

L O'Donnell, D Rhodes, SJ Smith, DJ Merriner… - PLoS …, 2012 - journals.plos.org
Katanin is an evolutionarily conserved microtubule-severing complex implicated in multiple
aspects of microtubule dynamics. Katanin consists of a p60 severing enzyme and a p80 …

CRISP2 is a regulator of multiple aspects of sperm function and male fertility

S Lim, M Kierzek, AE O'Connor, C Brenker… - …, 2019 - academic.oup.com
The cysteine-rich secretory proteins (CRISPs) are a group of proteins that show a
pronounced expression biased to the male reproductive tract. Although sperm encounter …