Box–Behnken design: optimization of Proanthocyanidin-loaded Transferosomes as an effective therapeutic approach for osteoarthritis

N Tamilarasan, BM Yasmin, P Anitha, H Umme… - Nanomaterials, 2022 - mdpi.com
Transferosomes are one of the vesicular carriers that have received extensive research and
attention recently because of their capacity to get beyond the barriers posed by the stratum …

Biopolymer collagen-chitosan scaffold containing Aloe vera for chondrogenic efficacy on cartilage tissue engineering

P Jithendra, JMM Mohamed, D Annamalai… - International Journal of …, 2023 - Elsevier
The chondrogenic efficacy of aloe vera blended collagen-chitosan (COL-CS-AV) porous
scaffold was investigated using articular chondrocytes in a standard condition …

Preparation of memantine-loaded chitosan nanocrystals: in vitro and ex vivo toxicity analysis

MA Saleh, JMM Mohamed, JJ Ruby, S Kanthiah… - Crystals, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with unmet medical
need, and is the leading cause of age-related dementia affecting millions of people …

Drug Nanocrystals: A Delivery Channel for Antiviral Therapies

A Chaturvedi, S Sharma, R Shukla - AAPS PharmSciTech, 2024 - Springer
Viral infections represent a significant threat to global health due to their highly
communicable and potentially lethal nature. Conventional antiviral interventions encounter …

Design, Physical Characterizations, and Biocompatibility of Cationic Solid Lipid Nanoparticles in HCT-116 and 16-HBE Cells: A Preliminary Study

A Alamri, A Alqahtani, T Alqahtani, A Al Fatease… - Molecules, 2023 - mdpi.com
In this study, pEGFP-LUC was used as a model plasmid and three distinct cationic lipids
(dioleyloxy-propyl-trimethylammonium chloride [DOTMA], dioleoyl trimethylammonium …

Exploring nalbuphine loaded chitosan nanoparticles for effective pain management through intranasal administration: a comparative study

K Khanna, N Sharma, R Karwasra, A Kumar… - Journal of Drug …, 2024 - Taylor & Francis
Background Intranasal drug delivery shows potential for brain access via olfactory and
trigeminal routes. Purpose This work aimed to ensure brain availability of nalbuphine via the …

Fabrication, Characterization and In Vitro Cell Cytotoxicity of ZnO Nanoparticles on MDA‐MB 231 Breast Cancer Cell Line

A Kumar Janakiraman, Z Yin Wong, Z Cheng… - …, 2023 - Wiley Online Library
The intention of this study was to prepare zinc oxide nanoparticles (ZnO‐NPs) via bottom‐up
approach and evaluate their physiochemical, antimicrobial and anticancer properties. ZnO …

Sunlight-assisted green synthesis of silver nanoparticles using Zizania latifolia extract: toward antimicrobial applications

V Satheesh, JMM Mohamed, M El-Sherbiny… - Biomass Conversion …, 2022 - Springer
The present study was focused on green synthesis of silver nanoparticles against pathogens
of both gram-positive and gram-negative classes. Green synthesis of silver nanoparticles …

Bioassessment of the inflammatory response of macrophages to collagen-chitosan scaffold blended with Aloe vera

P Jithendra, D Annamalai, HA Ebrahim… - Biomass Conversion …, 2024 - Springer
The in vitro macrophage response on Aloe vera-blended collagen-chitosan (COL-CS-AV)
scaffold was studied using Murine Raw 264 macrophage cells. The cells were cultured on 1 …

Biodegradable Polymers-Based Smart Nanocrystals for Loxoprofen Delivery with Enhanced Solubility: Design, Fabrication and Physical Characterizations

BA Khan, H Khalid, MK Khan, KM Hosny, S Khan… - Polymers, 2022 - mdpi.com
Nanocrystals are carrier-free, submicron-sized, colloidal drug delivery systems with particle
sizes in the mean nanometer range. Nanocrystals have high bioavailability and fast …