Histones are DNA‐binding basic proteins found in chromosomes. After the histone
translation, its amino tail undergoes various modifications, such as methylation, acetylation …

Metabolites are intermediate products of cellular metabolism catalysed by various enzymes.
Metabolic remodelling, as a biochemical fingerprint of cancer cells, causes abnormal …

Lysine succinylation is one of the major post-translational modifications occurring on
histones and is believed to have significant roles in regulating chromatin structure and …

Lysine lactylation (Kla) links metabolism and gene regulation and plays a key role in
multiple biological processes. However, the regulatory mechanism and functional …

Histone lysine crotonylation was first identified as a new type of post-translational
modification in 2011. In recent years, prominent progress has been made in the study of …

Lysine benzoylation (Kbz) is a newly discovered protein post-translational modification
(PTM). This PTM can be stimulated by benzoate and contributes to gene expression …

Legionella pneumophila replicates intracellularly by secreting effectors via a type IV
secretion system. One of these effectors is a eukaryotic methyltransferase (RomA) that …

CD8+ tissue-resident memory T (Trm) cells and tumor-infiltrating lymphocytes (TIL) regulate
tumor immunity and immune surveillance. Characterization of Trm cells and TILs could help …

Accurate and integral cellular DNA replication is modulated by multiple replication‐
associated proteins, which is fundamental to preserve genome stability. Furthermore …

Post-translational modifications (PTM) are covalent modifications of proteins or peptides
caused by proteolytic cleavage or the attachment of moieties to one or more amino acids …