Sleep disturbances are common in various neurological pathologies, including amyotrophic
lateral sclerosis (ALS), multiple system atrophy (MSA), hereditary ataxias, Huntington's …

Circadian blood pressure (BP) rhythm is important for the maintenance of healthy daily life,
and its disruption is associated with poor outcomes. Cardiovascular autonomic failure is …

Synucleinopathies are a group of neurodegenerative disorders, classically characterized by
the accumulation of aggregated alpha synuclein (aSyn) in the central nervous system …

Background The longitudinal dynamics of neurofilament light chain (NfL) in multiple system
atrophy (MSA) were incompletely illuminated. This study aimed to explore whether the …

In this article we have reviewed the potential role of coenzyme Q10 (CoQ10) in the
pathogenesis and treatment of a number of less common age-related disorders, for many of …

Background We here report the pre-diagnostic clinical presentations of patients with Multiple
System Atrophy (MSA) from analysis of a large routine clinical care database. Methods Data …

MSA is a rapidly progressive neurodegenerative disease characterized by a combination of
autonomic failure and motor symptoms. MSA is often misdiagnosed as the initial …

The cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) is a late-
onset and recessively inherited ataxia. For many years, CANVAS has been diagnosed …

Parkinson's disease (PD) is the second most common type of neurogenerative disease
among middleaged and older people, characterized by aggregation of alpha-synuclein and …

The objective of the study was to characterize the pattern of cognitive dysfunction in patients
with multiple system atrophy (MSA) applying a standardized neuropsychological …