Current approaches and developments in transcript profiling of the human placenta
BACKGROUND The placenta is the active interface between mother and foetus, bearing the
molecular marks of rapid development and exposures in utero. The placenta is routinely …
molecular marks of rapid development and exposures in utero. The placenta is routinely …
[HTML][HTML] Alternative splicing of lncRNAs in human diseases
J Chen, Y Liu, J Min, H Wang, F Li, C Xu… - American journal of …, 2021 - ncbi.nlm.nih.gov
Alternative splicing (AS), a vital post-transcription process for eukaryote gene expression
regulating, can efficiently improve gene utilization and increase the variety of RNA …
regulating, can efficiently improve gene utilization and increase the variety of RNA …
Transcriptional regulation: Molecules, involved mechanisms, and misregulation
A Casamassimi, A Ciccodicola - International journal of molecular …, 2019 - mdpi.com
Transcriptional regulation is a critical biological process that allows the cell or an organism
to respond to a variety of intra-and extra-cellular signals, to define cell identity during …
to respond to a variety of intra-and extra-cellular signals, to define cell identity during …
Placenta transcriptome profiling in intrauterine growth restriction (IUGR)
M Majewska, A Lipka, L Paukszto… - International journal of …, 2019 - mdpi.com
Intrauterine growth restriction (IUGR) is a serious pathological complication associated with
compromised fetal development during pregnancy. The aim of the study was to broaden …
compromised fetal development during pregnancy. The aim of the study was to broaden …
Preeclampsia-associated lncRNA INHBA-AS1 regulates the proliferation, invasion, and migration of placental trophoblast cells
Preeclampsia is believed to be caused by impaired placentation with insufficient trophoblast
invasion, leading to impaired uterine spiral artery remodeling and angiogenesis. However …
invasion, leading to impaired uterine spiral artery remodeling and angiogenesis. However …
The role of non-coding RNAs in the human placenta
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs,
and species, which has been broadly recognized since the human ENCODE project and …
and species, which has been broadly recognized since the human ENCODE project and …
[HTML][HTML] Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
Background Among children, sex-specific differences in disease prevalence, age of onset,
and susceptibility have been observed in health conditions including asthma, immune …
and susceptibility have been observed in health conditions including asthma, immune …
Sex-specific up-regulation of lncRNAs in peripheral blood of patients with schizophrenia
Schizophrenia as a common disabling psychiatric disorder has been associated with
dysregulation of several genes and pathways among them are those being regulated by …
dysregulation of several genes and pathways among them are those being regulated by …
Silencing TTTY15 mitigates hypoxia-induced mitochondrial energy metabolism dysfunction and cardiomyocytes apoptosis via TTTY15/let-7i-5p and TLR3/NF-κB …
H Zhang, X Zou, F Liu - Cellular Signalling, 2020 - Elsevier
Noncoding RNAs are interweaved in pathological processes in myocardial ischemia (MI),
such as long noncoding RNA (lncRNA) and microRNAs (miRNAs). The aim of this study was …
such as long noncoding RNA (lncRNA) and microRNAs (miRNAs). The aim of this study was …
Expression of long noncoding RNAs in the ovarian granulosa cells of women with diminished ovarian reserve using high-throughput sequencing
L Dong, X Xin, HM Chang, PCK Leung, C Yu… - Journal of Ovarian …, 2022 - Springer
Background Infertility is a global reproductive-health problem, and diminished ovarian
reserve (DOR) is one of the common causes of female infertility. Long noncoding RNAs …
reserve (DOR) is one of the common causes of female infertility. Long noncoding RNAs …