Antimicrobial peptides: Their role as infection‐selective tracers for molecular imaging
Antimicrobial peptides (AMPs) are a heterogeneous class of compounds found in a variety
of organisms including humans and, so far, hundreds of these structures have been isolated …
of organisms including humans and, so far, hundreds of these structures have been isolated …
[HTML][HTML] Bone infection site targeting nanoparticle-antibiotics delivery vehicle to enhance treatment efficacy of orthopedic implant related infection
Orthopedic implants account for 99% of orthopedic surgeries, however, orthopedic implant-
related infection is one of the most serious complications owing to the potential for limb …
related infection is one of the most serious complications owing to the potential for limb …
Recent advances in prevention, detection and treatment in prosthetic joint infections of bioactive materials
H Xie, Y Liu, H An, J Yi, C Li, X Wang… - … in Bioengineering and …, 2022 - frontiersin.org
Prosthetic joint infection (PJI) is often considered as one of the most common but
catastrophic complications after artificial joint replacement, which can lead to surgical failure …
catastrophic complications after artificial joint replacement, which can lead to surgical failure …
Antibacterial efficacy of gold and silver nanoparticles functionalized with the ubiquicidin (29–41) antimicrobial peptide
E Morales-Avila, G Ferro-Flores… - Journal of …, 2017 - Wiley Online Library
Recent studies have demonstrated that drug antimicrobial activity is enhanced when
metallic nanoparticles are used as an inorganic support, obtaining synergic effects against …
metallic nanoparticles are used as an inorganic support, obtaining synergic effects against …
Ubiquicidin-derived peptides selectively interact with the anionic phospholipid membrane
Ubiquicidin (UBI)/ribosomal protein S30 (RS30) is an intracellular protein with antimicrobial
activities against various pathogens. UBI (29–41) and UBI (31–38) are two crucial peptides …
activities against various pathogens. UBI (29–41) and UBI (31–38) are two crucial peptides …
Pathogen-specific bacterial imaging in nuclear medicine
AA Ordonez, SK Jain - Seminars in nuclear medicine, 2018 - Elsevier
When serious infections are suspected, patients are often treated empirically with broad-
spectrum antibiotics while awaiting results that provide information on the bacterial class …
spectrum antibiotics while awaiting results that provide information on the bacterial class …
Imaging of bacteria with radiolabeled ubiquicidin by SPECT and PET techniques
G Ferro-Flores, MA Avila-Rodríguez… - Clinical and …, 2016 - Springer
The ability to differentiate infection from sterile inflammation and monitor antimicrobial
therapy against multidrug-resistant pathogens through imaging of bacteria with radiolabeled …
therapy against multidrug-resistant pathogens through imaging of bacteria with radiolabeled …
Current status of SPECT radiopharmaceuticals for specific bacteria imaging
Imaging infection still represents a challenge for researchers. Despite nuclear medicine
(NM) offers valuable tools able to discriminate between infections and inflammation, there is …
(NM) offers valuable tools able to discriminate between infections and inflammation, there is …
Evaluation of 68Ga-DOTA-Ubiquicidin (29–41) for imaging Staphylococcus aureus (Staph A) infection and turpentine-induced inflammation in a preclinical setting
DK Boddeti, V Kumar - World Journal of Nuclear Medicine, 2021 - thieme-connect.com
Synthetic antimicrobial peptide fragment, 99m Tc-Ubiquicidin 29–41, is shown to be
sensitive and also specific for imaging bacterial infections. We undertook this study to …
sensitive and also specific for imaging bacterial infections. We undertook this study to …
[PDF][PDF] Current status of and perspectives on radiolabelled Ubiquicidin 29-41 derivatives for bacterial infection imaging
Y Jiang, J Zhang - Mini-Rev. Med. Chem, 2023 - researchgate.net
Bacterial infection is one of the most common causes of morbidity and death worldwide.
Distinguishing infection from sterile inflammation has been of great significance. As an …
Distinguishing infection from sterile inflammation has been of great significance. As an …