Investigation of the toxicity triggered by chemicals on the human brain has traditionally relied
on approaches using rodent in vivo models and in vitro cell models including primary …

Globally, the central nervous system (CNS) disorders appear as the most critical
pathological threat with no proper cure. Alzheimer's disease (AD) is one such condition …

Amyotrophic lateral sclerosis (ALS) is a complex disease that leads to motor neuron death.
Despite heritability estimates of 52%, genome-wide association studies (GWASs) have …

Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the
molecular and cellular processes involved in disorders of the nervous system. Adapting …

Human dental pulp stem cells (hDPSCs) have increasingly gained interest as a potential
therapy for nerve regeneration in medicine and dentistry, however their neurogenic potential …

The human SH-SY5Y neuroblastoma cell line is widely used in neuroscience research as a
neuronal cell model. Following differentiation to a neuron-like state, SH-SY5Y cells become …

We prepared cellulose nanofibrils-based (CNF), alginate-based and single-walled carbon
nanotubes (SWCNT)-based inks for freeform reversible embedding hydrogel (FRESH) 3D …

Our present work demonstrates the successful design and synthesis of a new class of
compounds based upon a multitargeted directed ligand design approach to discover new …

Luteolin is one of the most common flavonoids present in edible plants and its potential
benefits to the central nervous system include decrease of microglia activation, neuronal …

Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, is associated with
neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and …