The SH-SY5Y human neuroblastoma cell line, a relevant in vitro cell model for investigating neurotoxicology in human: Focus on organic pollutants
L Lopez-Suarez, S Al Awabdh, X Coumoul, C Chauvet - Neurotoxicology, 2022 - Elsevier
Investigation of the toxicity triggered by chemicals on the human brain has traditionally relied
on approaches using rodent in vivo models and in vitro cell models including primary …
on approaches using rodent in vivo models and in vitro cell models including primary …
Recent expansions on cellular models to uncover the scientific barriers towards drug development for Alzheimer's disease
Globally, the central nervous system (CNS) disorders appear as the most critical
pathological threat with no proper cure. Alzheimer's disease (AD) is one such condition …
pathological threat with no proper cure. Alzheimer's disease (AD) is one such condition …
Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a complex disease that leads to motor neuron death.
Despite heritability estimates of 52%, genome-wide association studies (GWASs) have …
Despite heritability estimates of 52%, genome-wide association studies (GWASs) have …
Optimised techniques for high-throughput screening of differentiated SH-SY5Y cells and application for neurite outgrowth assays
Neuronal models are a crucial tool in neuroscientific research, helping to elucidate the
molecular and cellular processes involved in disorders of the nervous system. Adapting …
molecular and cellular processes involved in disorders of the nervous system. Adapting …
Exploring the neurogenic differentiation of human dental pulp stem cells
Human dental pulp stem cells (hDPSCs) have increasingly gained interest as a potential
therapy for nerve regeneration in medicine and dentistry, however their neurogenic potential …
therapy for nerve regeneration in medicine and dentistry, however their neurogenic potential …
A novel method for generating glutamatergic SH-SY5Y neuron-like cells utilizing B-27 supplement
ER Martin, J Gandawijaya… - Frontiers in Pharmacology, 2022 - frontiersin.org
The human SH-SY5Y neuroblastoma cell line is widely used in neuroscience research as a
neuronal cell model. Following differentiation to a neuron-like state, SH-SY5Y cells become …
neuronal cell model. Following differentiation to a neuron-like state, SH-SY5Y cells become …
3D printed conductive nanocellulose scaffolds for the differentiation of human neuroblastoma cells
M Bordoni, E Karabulut, V Kuzmenko, V Fantini… - Cells, 2020 - mdpi.com
We prepared cellulose nanofibrils-based (CNF), alginate-based and single-walled carbon
nanotubes (SWCNT)-based inks for freeform reversible embedding hydrogel (FRESH) 3D …
nanotubes (SWCNT)-based inks for freeform reversible embedding hydrogel (FRESH) 3D …
Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands for …
Our present work demonstrates the successful design and synthesis of a new class of
compounds based upon a multitargeted directed ligand design approach to discover new …
compounds based upon a multitargeted directed ligand design approach to discover new …
Neuroprotective effect of luteolin-7-O-glucoside against 6-OHDA-induced damage in undifferentiated and RA-differentiated SH-SY5Y cells
SCH Rehfeldt, J Silva, C Alves, S Pinteus… - International Journal of …, 2022 - mdpi.com
Luteolin is one of the most common flavonoids present in edible plants and its potential
benefits to the central nervous system include decrease of microglia activation, neuronal …
benefits to the central nervous system include decrease of microglia activation, neuronal …
P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontitis, is associated with
neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and …
neuroinflammation. Periodontal disease increases with age; 70.1% of adults 65 years and …