Fruit and vegetables (F&V) have been a cornerstone of healthy dietary recommendations;
the 2015–2020 US Dietary Guidelines for Americans recommend that F&V constitute one …

A strong and expanding evidence base supports the influence of gut microbiota in human
metabolism. Altered glucose homeostasis is associated with altered gut microbiota, and is …

The gastrointestinal tract contains trillions of microbes (collectively known as the gut
microbiota) that play essential roles in host physiology and health. Studies from our group …

Glucose metabolism is normally regulated by a feedback loop including islet β cells and
insulin-sensitive tissues, in which tissue sensitivity to insulin affects magnitude of β-cell …

The worldwide prevalence of obesity and type 2 diabetes mellitus (T2DM) continues to rise
at an alarming pace. Recently the potential role of the gut microbiome in these metabolic …

Hyperuricemia (HUA) is induced by abnormal purine metabolism and elevated serum uric
acid (UA) concentrations, and it is often accompanied by inflammatory responses and …

Gut bacteria occupy the interface between the organism and the external environment,
contributing to homeostasis and disease. Yet, the causal role of the gut microbiota during …

Maintenance of healthy human metabolism depends on a symbiotic consortium among
bacteria, archaea, viruses, fungi, and host eukaryotic cells throughout the human …

Alterations in intestinal microbiota are associated with obesity and insulin resistance. We
studied the effects of infusing intestinal microbiota from lean donors to male recipients with …

Gastrointestinal transit time may be an important determinant of glucose homeostasis and
metabolic health through effects on nutrient absorption and microbial composition, among …