Background One of the criteria to objectively prioritize merozoite antigens for malaria
vaccine development is the demonstration that naturally acquired antibodies are associated …

School‐age children have attracted relatively little attention as a group in need of special
measures to protect them against malaria. However, increasing success in lowering the …

Humoral immunity consists of pre-existing antibodies expressed by long-lived plasma cells
and rapidly reactive memory B cells (MBC). Recent studies of MBC development and …

Most studies on human immunity to malaria have focused on the roles of immunoglobulin G
(IgG), whereas the roles of IgM remain undefined. Analyzing multiple human cohorts to …

Malaria is a leading cause of mortality and morbidity globally, and effective vaccines are
urgently needed. Malaria vaccine approaches can be broadly grouped as pre‐erythrocytic …

Some new cassava accessions have been developed and released because of their high
yield, resistance to disease, adaptability to wider ecological environment, and less cost of …

A double blind, randomized, controlled Phase 2 clinical trial was conducted to assess the
safety, immunogenicity, and biologic impact of the vaccine candidate Apical Membrane …

IgG antibodies play a role in malaria immunity, but whether and how IgM protects from
malaria and the biology of Plasmodium falciparum (Pf)–specific IgM B cells is unclear. In a …

Naturally acquired humoral immunity to the malarial parasite Plasmodium falciparum can
protect against disease, although the precise mechanisms remain unclear. Although …

Over the last 30 years, evidence has been gathered suggesting that merozoite surface
protein 1 (MSP1) is a target of protective immunity against malaria. In a variety of …