Multiple sclerosis (MS) is an immune-mediated, chronic inflammatory, demyelinating, and
neurodegenerative disease of the central nervous system (CNS). Immune cell infiltration can …

Sinomenine is a natural compound extracted from the medicinal plant Sinomenium acutum.
Its supplementation has been shown to present benefits in a variety of animal models of …

An association of melatonin levels with age disease initiation of autoimmune diseases and
pineal calcification was reported while an inverse association between melatonin levels and …

Axon degeneration is a prominent feature of the injured nervous system, occurs across
neurological diseases, and drives functional loss in neural circuits. We have seen a …

Despite advances in the treatment of chronic inflammatory demyelinating
polyradiculoneuropathy (CIDP) and other common autoimmune neuropathies (AN), still …

Recent studies have strengthened the evidence for Epstein–Barr Virus (EBV) as an
important contributing factor in the development of multiple sclerosis (MS). Chronic …

Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central
nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal …

Multiple sclerosis (MS) is a multifaceted, complex and chronic neurological disease that
leads to motor, sensory and cognitive deficits. MS symptoms are unpredictable and …

Mitochondria are vital organelles in eukaryotic cells that control diverse physiological
processes related to energy production, calcium homeostasis, the generation of reactive …

Abstract Sphingosine-1-phosphate receptor (S1PR) signaling regulates diverse
pathophysiological processes in the central nervous system. The role of S1PR signaling in …