Blood transfusion is the key to life in case of traumatic emergencies, surgeries and in several
pathological conditions. An important goal of whole blood or red blood cell transfusion is the …

Significance: The worldwide blood shortage has generated a significant demand for
alternatives to whole blood and packed red blood cells for use in transfusion therapy. One …

The α-and β-globins of human haemoglobin Hba were co-expressed in transgenic tobacco
plants, leading to the production of functional tetrameric haemoglobin. Following …

Due to limitations associated with whole blood for transfusions (antigen compatibility,
transmission of infections, supply and storage), the use of cell-free hemoglobin as an …

The development of oxygen-carrying blood substitutes has progressed significantly in the
last decade with phase I and phase II clinical trials of both hemoglobin-based and …

This is the first book that provides a comprehensive review of the entire area of artificial cells.
The author, a pioneer of the field, invented the first artificial cells some 50 years ago and has …

Background: Potential blood substitutes can be based on hemoglobin. Two problems must
be overcome with acellular hemoglobin-based blood substitutes, however: the oxygen …

Concerns about the infectious and immunosuppressive risks of allogeneic blood products
persist, and the increased disproportion of blood donation and consumption has reinforced …

Blood is a liquid tissue in which dissolved with abundant chemical factors and millions of
different cells The reduction of unwanted side effects, especially diseases that emerge …

Chemically modified haemoglobin solutions represent a potential alternative to the
transfusion of donor blood. The theoretical advantages of these products include an oxygen …