[HTML][HTML] Hybridization facilitates adaptive evolution in two major fungal pathogens

H Samarasinghe, M You, TS Jenkinson, J Xu… - Genes, 2020 - mdpi.com
Hybridization is increasingly recognized as an important force impacting adaptation and
evolution in many lineages of fungi. During hybridization, divergent genomes and alleles are …

[HTML][HTML] Analyses of the Global Multilocus Genotypes of the Human Pathogenic Yeast Cryptococcus neoformans Species Complex

M Hitchcock, J Xu - Genes, 2022 - mdpi.com
Cryptococcus neoformans species complex (CNSC) is a globally distributed human
opportunistic yeast pathogen consisting of five major molecular types (VNI, VNII, VNB, VNIII …

[HTML][HTML] Factors enforcing the species boundary between the human pathogens Cryptococcus neoformans and Cryptococcus deneoformans

SJ Priest, MA Coelho, V Mixão, SA Clancey, Y Xu… - PLoS …, 2021 - journals.plos.org
Hybridization has resulted in the origin and variation in extant species, and hybrids continue
to arise despite pre-and post-zygotic barriers that limit their formation and evolutionary …

[HTML][HTML] Multi-locus sequence typing and phylogenetics of Cryptococcus neoformans AD hybrids

M Cogliati, PE Chidebelu, M Hitchcock, M Chen… - Fungal Genetics and …, 2024 - Elsevier
Hybrid AD strains of the human pathogenic Cryptococcus neoformans species complex
have been reported from many parts of the world. However, their origin, diversity, and …

Clonal evolution in serially passaged Cryptococcus neoformans × deneoformans hybrids reveals a heterogenous landscape of genomic change

LA Michelotti, S Sun, J Heitman, TY James - Genetics, 2022 - academic.oup.com
Cryptococcus neoformans× deneoformans hybrids (also known as serotype AD hybrids) are
basidiomycete yeasts that are common in a clinical setting. Like many hybrids, the AD …

Phenotypic Plasticity in the Productions of Virulence Factors Within and Among Serotypes in the Cryptococcus neoformans Species Complex

Y Iyengar, J Xu - Mycopathologia, 2022 - Springer
The Cryptococcus neoformans species complex (CNSC) is a common opportunistic human
fungal pathogen and the most frequent cause of fungal meningitis. There are three major …

Roles of RNA Interference and DNA Mismatch Repair in Maintaining Genomic Integrity in Cryptococcus Pathogens

SJ Priest - 2022 - search.proquest.com
Microorganisms must regulate genomic stability to strike a balance between excessive
deleterious mutation and evolutionary stagnation to successfully compete and endure within …