Articular cartilage is susceptible to damage but hard to self-repair due to its avascular
nature. Traditional treatment methods are not able to produce satisfactory effects …

With the continuous improvement of human technology, the medical field has gradually
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …

Adipogenesis, osteogenesis and chondrogenesis of human mesenchymal stem/stromal
cells (MSC) are complex and highly regulated processes. Over the years, several studies …

Effective regeneration of bone defects often presents significant challenges, particularly in
patients with decreased tissue regeneration capacity due to extensive trauma, disease …

Abstract Background Mesenchymal stromal cells (MSCs) have been introduced as
promising cell source for regenerative medicine. Besides their multilineage differentiation …

Articular cartilage is susceptible to damage, but its self‐repair is hindered by its avascular
nature. Traditional treatment methods are not able to achieve satisfactory repair effects, and …

Mesenchymal stromal cells nowadays emerge as a major player in the field of regenerative
medicine and translational research. They constitute, with their derived products, the most …

Multipotent mesenchymal stromal cells (MSCs) have been described as bone marrow
stromal cells, which can form cartilage, bone or hematopoietic supportive stroma. In 2006 …

Cartilage damage is the leading cause of osteoarthritis (OA), especially in an aging society.
Mimicking the native cartilage microenvironment for chondrogenic differentiation along with …

The goal of the present study is to identify the differential expression of circular RNA
(circRNA), miRNA, and piwi-interacting RNA (piRNA) after lineage commitment towards …