Epitope tagging
JW Jarvik, CA Telmer - Annual review of genetics, 1998 - annualreviews.org
▪ Abstract Epitope tagging is a recombinant DNA method by which a protein encoded by a
cloned gene is made immunoreactive to a known antibody. This review discusses the major …
cloned gene is made immunoreactive to a known antibody. This review discusses the major …
[HTML][HTML] A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers
JR Bischoff, L Anderson, Y Zhu, K Mossie, L Ng… - The EMBO …, 1998 - embopress.org
Genetic and biochemical studies in lower eukaryotes have identified several proteins that
ensure accurate segregation of chromosomes. These include the Drosophila aurora and …
ensure accurate segregation of chromosomes. These include the Drosophila aurora and …
Analyzing protein–protein interactions by quantitative mass spectrometry
Since most cellular processes depend on interactions between proteins, information about
protein–protein interactions (PPIs) provide valuable insights into protein function. Over the …
protein–protein interactions (PPIs) provide valuable insights into protein function. Over the …
Mammalian Suppressor-of-Fused modulates nuclear–cytoplasmic shuttling of GLI-1
P Kogerman, T Grimm, L Kogerman, D Krause… - Nature cell …, 1999 - nature.com
Abstract Sonic hedgehog, Patched and Gli are components of a mammalian signalling
pathway that has been conserved during evolution and which has a central role in the …
pathway that has been conserved during evolution and which has a central role in the …
Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.
R Kopan, EH Schroeter… - Proceedings of the …, 1996 - National Acad Sciences
Previous studies imply that the intracellular domain of Notch1 must translocate to the
nucleus for its activity. In this study, we demonstrate that a mNotch1 mutant protein that lacks …
nucleus for its activity. In this study, we demonstrate that a mNotch1 mutant protein that lacks …
Characterization of the interactions of α-catenin with α-actinin and β-catenin/plakoglobin
JE Nieset, AR Redfield, F Jin… - Journal of cell …, 1997 - journals.biologists.com
Cadherins are calcium-dependent, cell surface glycoproteins involved in cell-cell adhesion.
To function in cell-cell adhesion, the transmembrane cadherin molecule must be associated …
To function in cell-cell adhesion, the transmembrane cadherin molecule must be associated …
The monomer-binding orphan receptor Rev-Erb represses transcription as a dimer on a novel direct repeat
HP Harding, MA Lazar - Molecular and cellular biology, 1995 - Taylor & Francis
Rev-Erb is an orphan nuclear receptor which binds as a monomer to the thyroid/retinoic acid
receptor half-site AGGTCA flanked 5′ by an A/T-rich sequence, referred to here as a Rev …
receptor half-site AGGTCA flanked 5′ by an A/T-rich sequence, referred to here as a Rev …
Disruption of Trkb-mediated signaling induces disassembly of postsynaptic receptor clusters at neuromuscular junctions
M Gonzalez, FP Ruggiero, Q Chang, YJ Shi, MM Rich… - Neuron, 1999 - cell.com
Neurotrophins and tyrosine receptor kinase (Trk) receptors are expressed in skeletal
muscle, but it is unclear what functional role Trk-mediated signaling plays during postnatal …
muscle, but it is unclear what functional role Trk-mediated signaling plays during postnatal …
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiation
K Yamamoto, FW Quelle, WE Thierfelder… - … and cellular biology, 1994 - Taylor & Francis
Interferon regulation of gene expression is dependent on the tyrosine phosphorylation and
activation of the DNA-binding activity of two related proteins of 91 kDa (STAT1) and/or 113 …
activation of the DNA-binding activity of two related proteins of 91 kDa (STAT1) and/or 113 …
Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-Δ11b
CA Wilson, MN Payton, GS Elliott, FW Buaas… - Oncogene, 1997 - nature.com
The mechanism of BRCA1 tumor suppression in human breast and ovarian cells is the focus
of intense investigation. In this report, full length BRCA1 (230 kDa) introduced into cells with …
of intense investigation. In this report, full length BRCA1 (230 kDa) introduced into cells with …