[HTML][HTML] Cancer hallmarks, biomarkers and breast cancer molecular subtypes

X Dai, L Xiang, T Li, Z Bai - Journal of cancer, 2016 - ncbi.nlm.nih.gov
Breast cancer is a complex disease encompassing multiple tumor entities, each
characterized by distinct morphology, behavior and clinical implications. Besides estrogen …

Pathology of triple negative breast cancer

F Borri, A Granaglia - Seminars in cancer biology, 2021 - Elsevier
Triple negative breast cancer (TNBC) is a subtype of breast tumor lacking hormone
receptors expression and HER2 gene amplification and represents 24% of newly diagnosed …

[HTML][HTML] Understanding breast cancer–The long and winding road

KE Lukong - BBA clinical, 2017 - Elsevier
Background Despite a remarkable increase in the depth of our understanding and
management of breast cancer in the past 50 years, the disease is still a major public health …

[HTML][HTML] Triple-negative breast cancer: epidemiological considerations and recommendations

P Boyle - Annals of oncology, 2012 - Elsevier
Breast cancer is a major problem for global public health. Breast Cancer is the most
common incident form of cancer in women around the world. The incidence is increasing …

Chronic obstructive pulmonary disease phenotypes: the future of COPD

MLK Han, A Agusti, PM Calverley, BR Celli… - American journal of …, 2010 - atsjournals.org
Significant heterogeneity of clinical presentation and disease progression exists within
chronic obstructive pulmonary disease (COPD). Although FEV1 inadequately describes this …

[HTML][HTML] Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists

S Badve, DJ Dabbs, SJ Schnitt, FL Baehner, T Decker… - Modern pathology, 2011 - Elsevier
Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct
morphological features and clinical behaviors. Although morphology is often associated with …

Triple-negative breast cancer: disease entity or title of convenience?

L Carey, E Winer, G Viale, D Cameron… - Nature reviews Clinical …, 2010 - nature.com
This Review outlines the understanding and management of triple-negative breast cancer
(TNBC). TNBC shares morphological and genetic abnormalities with basal-like breast …

Collagen prolyl 4-hydroxylase 1 is essential for HIF-1α stabilization and TNBC chemoresistance

G Xiong, RL Stewart, J Chen, T Gao, TL Scott… - Nature …, 2018 - nature.com
Abstract Collagen prolyl 4-hydroxylase (P4H) expression and collagen hydroxylation in
cancer cells are necessary for breast cancer progression. Here, we show that P4H alpha 1 …

Value of Mismatch Repair, KRAS, and BRAF Mutations in Predicting Recurrence and Benefits From Chemotherapy in Colorectal Cancer

G Hutchins, K Southward, K Handley… - Journal of Clinical …, 2011 - ascopubs.org
Purpose It is uncertain whether modest benefits from adjuvant chemotherapy in stage II
colorectal cancer justify the toxicity, cost, and inconvenience. We investigated the usefulness …

Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis

M Pierobon, CL Frankenfeld - Breast cancer research and treatment, 2013 - Springer
Triple-negative breast cancer (TNBC) is a subtype of breast tumor with unique
characteristics in terms of clinical− pathological presentation, prognosis, and response to …