Sex/gender effects have been demonstrated for multiple aspects of addiction, with one of the
most commonly cited examples being the “telescoping effect” where women meet criteria …

Recent policy changes have led to significant increases in the use of cannabis for both
medical and recreational purposes. Although men are more likely to endorse past month …

The purpose of this review is to discuss ways to think about and study sex differences in
preclinical animal models. We use the framework of addiction, in which animal models have …

Toll-like receptors (TLRs) are components of the innate immune system that respond to
exogenous infectious ligands (pathogen-associated molecular patterns, PAMPs) and …

Gender-dependent differences in the rate of initiation and frequency of misuse of addicting
drugs have been widely described. Yet, men and women also differ in their propensity to …

Marijuana is the most widely used illicit drug in the US, and marijuana use by women is on
the rise. Women have been found to be more susceptible to the development of cannabinoid …

Rationale Animal studies have found robust sex differences in the pharmacokinetics and
pharmacodynamics of Δ 9-tetrahydrocannabinol (THC). However, the human evidence …

Background Women exhibit an accelerated progression from first cannabis use to cannabis
use disorder (CUD) and show pronounced negative clinical issues related to CUD relative to …

In humans as in animals, males and females are dissimilar in their genetic and hormonally
driven behaviour; they process information differently, perceive experience and emotions in …

Marijuana use among women is highly prevalent, but the societal conversation on marijuana
rarely focuses on how marijuana affects female reproduction and endocrinology. This article …