Abstract Purpose of Review The basophil activation test (BAT) using flow cytometry has
supplanted traditional methods of measuring basophil degranulation using histamine and …

IgG4, the least represented human IgG subclass in serum, is an intriguing antibody with
unique biological properties, such as the ability to undergo Fab‐arm exchange and limit …

Monoclonal antibodies (mAbs) have been used in the development of immunotherapies that
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …

The adaptive humoral immune response is responsible for the generation of antimicrobial
proteins known as immunoglobulin molecules or antibodies. Immunoglobulins provide a …

IgG4 is the least abundant IgG subclass in human serum, representing less than 5% of all
IgG. Increases in IgG4 occur following chronic exposure to antigen and are generally …

The prevalence of asthma has been rising steadily for several decades, and continues to be
a major public health and global economic burden due to both direct and indirect costs …

Background Allergen-specific IgG 4 (sIgG 4) antibodies are often associated with tolerance,
but sIgG 4 antibodies to causally relevant foods have been reported recently in adults with …

Background In a previously reported Co FAR study, 55 subjects with egg allergy underwent
randomized, placebo‐controlled egg oral immunotherapy (eOIT). Active treatment induced …

Oral immunotherapy (OIT) has demonstrated reproducibly successful desensitization in
patients with food allergy completing clinical trials and, in some studies, sustained …

Background We recently reported that 16 weeks of sublingual immunotherapy (SLIT) with
recombinant (r) Mal d 1, but not rBet v 1, significantly improved birch pollen–related apple …