Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions

PK Hota, M Buck - Cellular and Molecular Life Sciences, 2012 - Springer
Plexin transmembrane receptors and their semaphorin ligands, as well as their co-receptors
(Neuropilin, Integrin, VEGFR2, ErbB2, and Met kinase) are emerging as key regulatory …

The emerging role of class-3 semaphorins and their neuropilin receptors in oncology

P Nasarre, RM Gemmill, HA Drabkin - OncoTargets and therapy, 2014 - Taylor & Francis
The semaphorins, discovered over 20 years ago, are a large family of secreted or
transmembrane and glycophosphatidylinositol-anchored proteins initially identified as axon …

Collapsin response mediator proteins: their biological functions and pathophysiology in neuronal development and regeneration

F Nakamura, T Ohshima, Y Goshima - Frontiers in cellular …, 2020 - frontiersin.org
Collapsin response mediator proteins (CRMPs), which consist of five homologous cytosolic
proteins, are one of the major phosphoproteins in the developing nervous system. The …

Collapsin response mediator proteins regulate neuronal development and plasticity by switching their phosphorylation status

N Yamashita, Y Goshima - Molecular neurobiology, 2012 - Springer
Collapsin response mediator protein (CRMP) was originally identified as a molecule
involved in semaphorin3A signaling. CRMPs are now known to consist of five homologous …

Depalmitoylation by palmitoyl-protein thioesterase 1 in neuronal health and degeneration

KP Koster, A Yoshii - Frontiers in synaptic neuroscience, 2019 - frontiersin.org
Protein palmitoylation is the post-translational, reversible addition of a 16-carbon fatty acid,
palmitate, to proteins. Protein palmitoylation has recently garnered much attention, as it …

Tubulin-related cerebellar dysplasia: definition of a distinct pattern of cerebellar malformation

R Romaniello, F Arrigoni, E Panzeri, A Poretti… - European …, 2017 - Springer
Objective To determine the neuroimaging pattern of cerebellar dysplasia (CD) and other
posterior fossa morphological anomalies associated with mutations in tubulin genes and to …

Localized role of CRMP1 and CRMP2 in neurite outgrowth and growth cone steering

M Higurashi, M Iketani, K Takei… - Developmental …, 2012 - Wiley Online Library
Collapsin response mediator protein 1 (CRMP1) and CRMP2 have been known as
mediators of extracellular guidance cues such as semaphorin 3A and contribute to …

Comparative phosphoproteomic analysis of neonatal and adult murine brain

T Goswami, X Li, AM Smith, EM Luderowski… - …, 2012 - Wiley Online Library
Developmental processes are governed by diverse regulatory mechanisms including a suite
of signaling pathways employing reversible phosphorylation. With the advent of large‐scale …

[HTML][HTML] Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain

L Valek, A Häussler, S Dröse, P Eaton, K Schröder… - Redox Biology, 2017 - Elsevier
Cyclic GMP-dependent protein kinase 1 (PKG1) mediates presynaptic nociceptive long-term
potentiation (LTP) in the spinal cord and contributes to inflammatory pain in rodents but the …

Synapsin III acts downstream of semaphorin 3A/CDK5 signaling to regulate radial migration and orientation of pyramidal neurons in vivo

LE Perlini, J Szczurkowska, BA Ballif, A Piccini… - Cell reports, 2015 - cell.com
Synapsin III (SynIII) is a phosphoprotein that is highly expressed at early stages of neuronal
development. Whereas in vitro evidence suggests a role for SynIII in neuronal differentiation …