Nature's fat-burning machine: brown adipose tissue in a hibernating mammal
MA Ballinger, MT Andrews - Journal of Experimental Biology, 2018 - journals.biologists.com
Brown adipose tissue (BAT) is a unique thermogenic tissue in mammals that rapidly
produces heat via nonshivering thermogenesis. Small mammalian hibernators have evolved …
produces heat via nonshivering thermogenesis. Small mammalian hibernators have evolved …
Proteomics approaches shed new light on hibernation physiology
KR Grabek, SL Martin, AG Hindle - Journal of Comparative Physiology B, 2015 - Springer
The broad phylogenetic distribution and rapid phenotypic transitions of mammalian
hibernators imply that hibernation is accomplished by differential expression of common …
hibernators imply that hibernation is accomplished by differential expression of common …
Seasonal and regional differences in gene expression in the brain of a hibernating mammal
C Schwartz, M Hampton, MT Andrews - PloS one, 2013 - journals.plos.org
Mammalian hibernation presents a unique opportunity to study naturally occurring
neuroprotection. Hibernating ground squirrels undergo rapid and extreme physiological …
neuroprotection. Hibernating ground squirrels undergo rapid and extreme physiological …
Low body temperature governs the decline of circulating lymphocytes during hibernation through sphingosine-1-phosphate
Hibernation is an energy-conserving behavior consisting of periods of inhibited metabolism
('torpor') with lowered body temperature. Torpor bouts are interspersed by arousal periods …
('torpor') with lowered body temperature. Torpor bouts are interspersed by arousal periods …
Deep sequencing the transcriptome reveals seasonal adaptive mechanisms in a hibernating mammal
Mammalian hibernation is a complex phenotype involving metabolic rate reduction,
bradycardia, profound hypothermia, and a reliance on stored fat that allows the animal to …
bradycardia, profound hypothermia, and a reliance on stored fat that allows the animal to …
Transcriptomic analysis of brown adipose tissue across the physiological extremes of natural hibernation
We used RNAseq to generate a comprehensive transcriptome of Brown Adipose Tissue
(BAT) over the course of a year in the naturally hibernating thirteen-lined ground squirrel …
(BAT) over the course of a year in the naturally hibernating thirteen-lined ground squirrel …
Membrane Phospholipid Fatty Acid Composition Regulates Cardiac SERCA Activity in a Hibernator, the Syrian Hamster (Mesocricetus auratus)
Polyunsaturated fatty acids (PUFA) have strong effects on hibernation and daily torpor.
Increased dietary uptake of PUFA of the n-6 class, particularly of Linoleic acid (LA, C18: 2 n …
Increased dietary uptake of PUFA of the n-6 class, particularly of Linoleic acid (LA, C18: 2 n …
Genetic variation drives seasonal onset of hibernation in the 13-lined ground squirrel
KR Grabek, TF Cooke, LE Epperson, KK Spees… - Communications …, 2019 - nature.com
Hibernation in sciurid rodents is a dynamic phenotype timed by a circannual clock. When
housed in an animal facility, 13-lined ground squirrels exhibit variation in seasonal onset of …
housed in an animal facility, 13-lined ground squirrels exhibit variation in seasonal onset of …
Platelet dynamics during natural and pharmacologically induced torpor and forced hypothermia
EL de Vrij, PC Vogelaar, M Goris, MC Houwertjes… - PLoS …, 2014 - journals.plos.org
Hibernation is an energy-conserving behavior in winter characterized by two phases: torpor
and arousal. During torpor, markedly reduced metabolic activity results in inactivity and …
and arousal. During torpor, markedly reduced metabolic activity results in inactivity and …
Comparative transcriptomics of the garden dormouse hypothalamus during hibernation
E Haugg, J Borner, G Stalder, A Kübber‐Heiss… - FEBS Open …, 2024 - Wiley Online Library
Torpor or heterothermy is an energy‐saving mechanism used by endotherms to overcome
harsh environmental conditions. During winter, the garden dormouse (Eliomys quercinus) …
harsh environmental conditions. During winter, the garden dormouse (Eliomys quercinus) …