Aptamer bioinformatics
Aptamers are short nucleic acid sequences capable of specific, high-affinity molecular
binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential …
binding. They are isolated via SELEX (Systematic Evolution of Ligands by Exponential …
Computational Selection of RNA Aptamer against Angiopoietin‐2 and Experimental Evaluation
Angiogenesis plays a decisive role in the growth and spread of cancer and angiopoietin‐2
(Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of …
(Ang2) is in the spotlight of studies for its unique role in modulating angiogenesis. The aim of …
In-Silico Selection of Aptamer Targeting SARS-CoV-2 Spike Protein
Aptamers are single-stranded, short DNA or RNA oligonucleotides that can specifically bind
to various target molecules. To diagnose the infected cases of severe acute respiratory …
to various target molecules. To diagnose the infected cases of severe acute respiratory …
Thrombin inhibitory peptides derived from Mytilus edulis proteins: identification, molecular docking and in silico prediction of toxicity
L Feng, M Tu, M Qiao, F Fan, H Chen, W Song… - … Food Research and …, 2018 - Springer
Optimization of the thrombin inhibitory activities of different enzymatic hydrolysates was
conducted, and then an optimal hydrolysis condition by trypsin (5000 u/g) was determined …
conducted, and then an optimal hydrolysis condition by trypsin (5000 u/g) was determined …
Investigating interactions between proteins and nucleic acids by computational approaches
Molecular simulations are wildly used in studying many types of biomolecular interactions,
such as protein-protein interaction, drugreceptor interaction, protein-nucleic acid (NA) …
such as protein-protein interaction, drugreceptor interaction, protein-nucleic acid (NA) …
Computational Design of a New Aflatoxin B1 Aptamer in lieu of SELEX Technique
MY Ahmad Ghazy - bioRxiv, 2022 - biorxiv.org
Mycotoxins are extremely dangerous, and their detection in our environment, food and feed
is becoming increasingly important. Biosensors are being implemented heavily in mycotoxin …
is becoming increasingly important. Biosensors are being implemented heavily in mycotoxin …
A Study on the Binding Ability of Truncated Aptamers for the Prostate Specific Antigen Using Both Computational and Experimental Approaches
HT Lin, W Yang, WY Su, CJ Chan, WY Chen… - … and Applications (FC …, 2018 - Springer
Prostate-specific antigen (PSA) test is a commonly used clinical examination to evaluate the
risk of prostate cancer, with the antibodies used normally as the recognition molecules for …
risk of prostate cancer, with the antibodies used normally as the recognition molecules for …
The Selection of DNA Aptamers Against the Fc Region of Human IgG
Aptamers can bind with various kinds of target molecules and therefore they have highly
potential for using in the therapeutic, diagnostic, biosensing, purification applications, etc …
potential for using in the therapeutic, diagnostic, biosensing, purification applications, etc …