Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor involved in
homeostatic regulation of normal cells and carcinogenesis of epithelial malignancies. With …

Radiotherapy has been used in the clinic for more than one century and it is recognized as
one of the main methods in the treatment of malignant tumors. Signal Transducers and …

Epidermal growth factor receptor (EGFR) gene amplification and activating mutations are
common findings in glioblastomas. EGFR is at the top of a downstream signaling cascade …

Background Photoimmunotherapy involves targeted delivery of photosensitizers via an
antibody conjugate (ie, photoimmunoconjugate, PIC) followed by light activation for selective …

ABSTRACT DNA damage plays a key role in various biological processes involved in
malignant disease, the role of the DNA damage repair gene EME1 (essential meiotic …

A number of solid tumors are treated with radiation therapy (RT) as a curative modality. At
the same time, for certain types of cancers the applicable doses of RT are not high enough …

Chromosomal instability (CIN) can be a driver of tumorigenesis but is also a promising
therapeutic target for cancer associated with poor prognosis such as triple negative breast …

Glioblastoma multiforme is the most aggressive primary brain tumor. Treatment is largely
palliative, with current strategies unable to prevent inevitable tumor recurrence. Implantable …

目的探讨减数分裂内切酶1 (EME1) 在肝癌组织中的表达及其对肝癌细胞生物学行为的影响.
方法筛选TCGA 数据库肝癌样本中的差异表达基因. 采用免疫组化和Western Blot 分析EME1 …

OBJECTIVE: Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer,
and its molecular pathogenesis is unclear. In this study, we investigated the prognostic value …