Personal utility in genomic testing: a systematic literature review

JN Kohler, E Turbitt, BB Biesecker - European Journal of Human …, 2017 - nature.com
Researchers and clinicians refer to outcomes of genomic testing that extend beyond clinical
utility as 'personal utility'. No systematic delineation of personal utility exists, making it …

Clinical application of next-generation sequencing to the practice of neurology

J Rexach, H Lee, JA Martinez-Agosto… - The Lancet …, 2019 - thelancet.com
Next-generation sequencing technologies allow for rapid and inexpensive large-scale
genomic analysis, creating unprecedented opportunities to integrate genomic data into the …

Legislation of direct-to-consumer genetic testing in Europe: a fragmented regulatory landscape

L Kalokairinou, HC Howard, S Slokenberga… - Journal of Community …, 2018 - Springer
Despite the increasing availability of direct-to-consumer (DTC) genetic testing, it is currently
unclear how such services are regulated in Europe, due to the lack of EU or national …

Whole exome and whole genome sequencing

D Bick, D Dimmock - Current opinion in pediatrics, 2011 - journals.lww.com
Whole exome and whole genome sequencing : Current Opinion in Pediatrics Whole exome
and whole genome sequencing : Current Opinion in Pediatrics Log in or Register Subscribe to …

The Human Genome Project, and recent advances in personalized genomics

BJ Wilson, SG Nicholls - Risk management and healthcare policy, 2015 - Taylor & Francis
The language of “personalized medicine” and “personal genomics” has now entered the
common lexicon. The idea of personalized medicine is the integration of genomic risk …

The evolution of public health genomics: exploring its past, present, and future

CM Molster, FL Bowman, GA Bilkey, AS Cho… - Frontiers in public …, 2018 - frontiersin.org
Public health genomics has evolved to responsibly integrate advancements in genomics
into the fields of personalized medicine and public health. Appropriate, effective and …

Applications of targeted gene capture and next-generation sequencing technologies in studies of human deafness and other genetic disabilities

X Lin, W Tang, S Ahmad, J Lu, CC Colby, J Zhu, Q Yu - Hearing research, 2012 - Elsevier
The goal of sequencing the entire human genome for $1000 is almost in sight. However, the
total costs including DNA sequencing, data management, and analysis to yield a clear data …

[HTML][HTML] Ethical, legal, and social implications of incorporating genomic information into electronic health records

R Hazin, KB Brothers, BA Malin, BA Koenig… - Genetics in …, 2013 - Elsevier
The inclusion of genomic data in the electronic health record raises important ethical, legal,
and social issues. In this article, we highlight these challenges and discuss potential …

Incorporating genomics into breast and prostate cancer screening: assessing the implications

S Chowdhury, T Dent, N Pashayan, A Hall… - GeNeTICs in …, 2013 - nature.com
Individual risk prediction and stratification based on polygenic profiling may be useful in
disease prevention. Risk-stratified population screening based on multiple factors including …

Ethical issues surrounding personalized medicine: a literature review

P Salari, B Larijani - Acta Medica Iranica, 2017 - acta.tums.ac.ir
More than a decade ago, personalized medicine was presented in modern medicine.
Personalized medicine means that the right drug should be prescribed for the right patient …