Regulation of VWF (von Willebrand factor) in inflammatory thrombosis
XD Manz, HJ Bogaard, J Aman - Arteriosclerosis, thrombosis, and …, 2022 - Am Heart Assoc
Increasing evidence indicates that inflammation promotes thrombosis via a VWF (von
Willebrand factor)-mediated mechanism. VWF plays an essential role in maintaining the …
Willebrand factor)-mediated mechanism. VWF plays an essential role in maintaining the …
New perspectives on the induction and acceleration of immune-associated thrombosis by PF4 and VWF
ZY Liu, MX Sun, MQ Hua, HX Zhang, GY Mu… - Frontiers in …, 2023 - frontiersin.org
Platelet factor 4 (PF4), also known as chemokine (CXC motif) ligand 4 (CXCL4), is a specific
protein synthesized from platelet α particles. The combination of PF4 and heparin to form …
protein synthesized from platelet α particles. The combination of PF4 and heparin to form …
Recombinant ADAMTS-13: first-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura
Safety, tolerability, and pharmacokinetics of recombinant ADAMTS-13 (a disintegrin and
metalloproteinase with a thrombospondin type 1 motif, member 13; BAX 930; SHP655) were …
metalloproteinase with a thrombospondin type 1 motif, member 13; BAX 930; SHP655) were …
Targeted antibody and cytokine cancer immunotherapies through collagen affinity
Cancer immunotherapy with immune checkpoint inhibitors (CPIs) and interleukin-2 (IL-2)
has demonstrated clinical efficacy but is frequently accompanied with severe adverse events …
has demonstrated clinical efficacy but is frequently accompanied with severe adverse events …
[HTML][HTML] Engineering an enthesis-like graft for rotator cuff repair: An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell …
C Chen, Q Shi, M Li, Y Chen, T Zhang, Y Xu, Y Liao… - Bioactive Materials, 2022 - Elsevier
Rotator cuff (RC) attaches to humerus across a triphasic yet continuous tissue zones (bone-
fibrocartilage-tendon), termed “enthesis”. Regrettably, rapid and functional enthesis …
fibrocartilage-tendon), termed “enthesis”. Regrettably, rapid and functional enthesis …
Molecular insights into the thrombotic and microvascular injury in placental endothelium of women with mild or severe COVID-19
A Flores-Pliego, J Miranda, S Vega-Torreblanca… - Cells, 2021 - mdpi.com
Clinical manifestations of coronavirus disease 2019 (COVID-19) in pregnant women are
diverse, and little is known of the impact of the disease on placental physiology. Severe …
diverse, and little is known of the impact of the disease on placental physiology. Severe …
[HTML][HTML] Endothelialization and smooth muscle cell regeneration capabilities of a bi-layered small diameter vascular graft for blood vessel reconstruction
MA Al Fahad, MS Rahaman, MSI Mahbub, M Park… - Materials & Design, 2023 - Elsevier
Despite the tremendous advances in the past few decades, the clinical problems associated
with low mechanical strength, thrombosis, and inadequate endothelialization still have not …
with low mechanical strength, thrombosis, and inadequate endothelialization still have not …
Prognostic value of von Willebrand factor and ADAMTS13 in patients with COVID-19: A systematic review and meta-analysis
X Xu, Y Feng, Y Jia, X Zhang, L Li, X Bai, L Jiao - Thrombosis Research, 2022 - Elsevier
Background Endotheliopathy and coagulopathy appear to be the main causes for critical
illness and death in patients with coronavirus disease 2019 (COVID-19). The adhesive …
illness and death in patients with coronavirus disease 2019 (COVID-19). The adhesive …
Functional decellularized fibrocartilaginous matrix graft for rotator cuff enthesis regeneration: a novel technique to avoid in-vitro loading of cells
C Chen, Y Chen, M Li, H Xiao, Q Shi, T Zhang, X Li… - Biomaterials, 2020 - Elsevier
Rapid and functional enthesis regeneration after rotator cuff tear (RCT) remains a challenge
in clinic. Current tissue-engineering strategies for solving this challenge are focused on …
in clinic. Current tissue-engineering strategies for solving this challenge are focused on …
Adenosine deaminase 1 overexpression enhances the antitumor efficacy of chimeric antigen receptor-engineered T cells
Chimeric antigen receptor (CAR) T cell therapy mediates unprecedented benefit in certain
leukemias and lymphomas, but has yet to achieve similar success in combating solid …
leukemias and lymphomas, but has yet to achieve similar success in combating solid …