Translational applications of hydrogels

S Correa, AK Grosskopf, H Lopez Hernandez… - Chemical …, 2021 - ACS Publications
Advances in hydrogel technology have unlocked unique and valuable capabilities that are
being applied to a diverse set of translational applications. Hydrogels perform functions …

Materials for oral delivery of proteins and peptides

TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …

[HTML][HTML] Subcutaneous administration of biotherapeutics: an overview of current challenges and opportunities

B Bittner, W Richter, J Schmidt - BioDrugs, 2018 - Springer
Subcutaneous delivery of biotherapeutics has become a valuable alternative to intravenous
administration across many disease areas. Although the pharmacokinetic profiles of …

Enhancing global access to cancer medicines

J Cortes, JM Perez‐García… - CA: a cancer journal …, 2020 - Wiley Online Library
Globally, cancer is the second leading cause of death, with numbers greatly exceeding
those for human immunodeficiency virus/acquired immunodeficiency syndrome …

The optimal choice of medication administration route regarding intravenous, intramuscular, and subcutaneous injection

J Jin, L Zhu, M Chen, H Xu, H Wang… - Patient preference …, 2015 - Taylor & Francis
Background Intravenous (IV), intramuscular (IM), and subcutaneous (SC) are the three most
frequently used injection routes in medication administration. Comparative studies of SC …

Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a …

AR Tan, SA Im, A Mattar, R Colomer… - The Lancet …, 2021 - thelancet.com
Background A subcutaneous formulation of pertuzumab and trastuzumab with recombinant
human hyaluronidase in one ready-to-use, fixed-dose combination vial (pertuzumab …

Trastuzumab in the treatment of breast cancer

S Maximiano, P Magalhaes, MP Guerreiro, M Morgado - BioDrugs, 2016 - Springer
Breast cancer (BC) is the most common cancer in women worldwide, and has an
undeniable negative impact on public health. The advent of molecular biology and …

A quantitative description for designing the extrudability of shear‐thinning physical hydrogels

H Lopez Hernandez, JW Souza… - Macromolecular …, 2021 - Wiley Online Library
Physically associated hydrogels (PHs) capable of reversible transitions between solid and
liquid‐like states have enabled novel strategies for 3D printing, therapeutic drug and cell …

Impact of breast cancer treatment on employment: results of a multicenter prospective cohort study (CANTO)

A Dumas, I Vaz Luis, T Bovagnet… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE Adverse effects of breast cancer treatment can negatively affect survivors' work
ability. Previous reports lacked detailed clinical data or health-related patient-reported …

[HTML][HTML] Patients' preferences for subcutaneous trastuzumab versus conventional intravenous infusion for the adjuvant treatment of HER2-positive early breast cancer …

X Pivot, J Gligorov, V Müller, G Curigliano, A Knoop… - Annals of oncology, 2014 - Elsevier
Background Patients with HER2-positive early breast cancer (EBC) preferred subcutaneous
(sc) trastuzumab, delivered via single-use injection device (SID), over the intravenous (iv) …