The colonic epithelium has both absorptive and secretory functions. The transport is
characterized by a net absorption of NaCl, short-chain fatty acids (SCFA), and water …

Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway
surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B …

Pilewski, Joseph M., and Raymond A. Frizzell. Role of CFTR in Airway Disease. Physiol.
Rev. 79, Suppl.: S215–S255, 1999.—Cystic fibrosis (CF) is caused by mutations in the gene …

Most airway mucus is produced by submucosal glands in response to neural signals. Gland
mucus traps microbes, inhibits their replication, and clears them from the airways. In cystic …

Cystic fibrosis (CF) airway cells, besides their well-known defect in cAMP-dependent Cl-
conductance, are characterized by an enhanced Na+ conductance. In this study we have …

Fluid and macromolecule secretion by submucosal glands in mammalian airways is
believed to be important in normal airway physiology and in the pathophysiology of cystic …

Prior studies have shown that fluid secretions from airway submucosal glands in cystic
fibrosis (CF) are reduced and hyperviscous, possibly contributing to the pathogenesis of CF …

Neuronal activity is required for the survival of specific populations of neurons, for the proper
synaptic organization of the visual and somatosensory cortex, and for learning and memory …

James M. Wilson, Editor serous cells will be higher (4). With regard to percent correction,
initial studies focused on this issue utilized monolayers of immortalized CF epithelial cells …

Both secretion and absorption of NaC1 are basic functions of epithelial cells. These
transport processes require polarized insertion of proteins specialized in ion transport to …