The raison d'être of meiosis is shuffling of genetic information via Mendelian segregation
and, within individual chromosomes, by DNA crossing-over. These outcomes are enabled …

Sexually reproducing eukaryotes use recombination between homologous chromosomes to
promote chromosome segregation during meiosis. Meiotic recombination is almost …

Programmed DNA double-strand break (DSB) formation is a crucial feature of meiosis in
most organisms. DSBs initiate recombination-mediated linking of homologous …

Key message Chromatin state, and dynamic loading of pro-crossover protein HEI10 at
recombination intermediates shape meiotic chromosome patterning in plants. Abstract …

The DNA double-strand breaks (DSBs) that initiate meiotic recombination are formed by an
evolutionarily conserved suite of factors that includes Rec114 and Mei4 (RM), which …

During meiotic prophase I, sister chromatids are arranged in a loop-base array along a
proteinaceous structure, called the meiotic chromosome axis. This structure is essential for …

Meiosis requires the formation of programmed DNA double strand breaks (DSBs), essential
for fertility and for generating genetic diversity. DSBs are induced by the catalytic activity of …

Meiosis is a highly conserved specialised cell division in sexual life cycles of eukaryotes,
forming the base of gene reshuffling, biological diversity and evolution. Understanding …

Meiosis is a specialized eukaryotic division that produces genetically diverse gametes for
sexual reproduction. During meiosis, homologous chromosomes pair and undergo …

Abstract Meiosis-specific Rec114− Mei4 and Mer2 complexes are thought to enable Spo11-
mediated DNA double-strand break (DSB) formation through a mechanism that involves …