Monitoring the redox status in multiple sclerosis

M Tanaka, L Vécsei - Biomedicines, 2020 - mdpi.com
Worldwide, over 2.2 million people suffer from multiple sclerosis (MS), a multifactorial
demyelinating disease of the central nervous system. MS is characterized by a wide range of …

Autoreactive lymphocytes in multiple sclerosis: Pathogenesis and treatment target

R Liu, S Du, L Zhao, S Jain, K Sahay… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS) characterized by destruction of the myelin sheath structure. The loss of myelin leads …

Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation

UK Zettl, PS Rommer, O Aktas, T Wagner… - Expert review of …, 2023 - Taylor & Francis
Introduction Interferon beta (IFN beta) preparations are an established group of drugs used
for immunomodulation in patients with multiple sclerosis (MS). Subcutaneously (sc) applied …

Integrative biochemical, proteomics and metabolomics cerebrospinal fluid biomarkers predict clinical conversion to multiple sclerosis

F Probert, T Yeo, Y Zhou, M Sealey, S Arora… - Brain …, 2021 - academic.oup.com
Eighty-five percent of multiple sclerosis cases begin with a discrete attack termed clinically
isolated syndrome, but 37% of clinically isolated syndrome patients do not experience a …

Re-evaluating the use of IFN-β and relapsing multiple sclerosis: safety, efficacy and place in therapy

CH Goldschmidt, LH Hua - Degenerative Neurological and …, 2020 - Taylor & Francis
The advent of interferon therapy for the treatment of multiple sclerosis (MS) was a massive
advancement in the field and changed the course of the disease. While the exact …

Gene therapy approaches in an autoimmune demyelinating disease: multiple sclerosis

MA Islam, S Kundu, R Hassan - Current Gene Therapy, 2019 - ingentaconnect.com
Multiple Sclerosis (MS) is the most common autoimmune demyelinating disease of the
Central Nervous System (CNS). It is a multifactorial disease which develops in an immune …

Preparation, characterization and in-vivo efficacy study of glatiramer acetate (GA)-hydrogel-microparticles as novel drug delivery system for GA in RRMS

N Hadidi, G Pazuki - Scientific Reports, 2022 - nature.com
Abstract Relapsing Remitting Multiple Sclerosis is a chronic Central nervous system
autoimmune disease. There is no absolute treatment for MS and the available remedies are …

NetConfer: a web application for comparative analysis of multiple biological networks

S Nagpal, KD Baksi, BK Kuntal, SS Mande - BMC biology, 2020 - Springer
Background Most biological experiments are inherently designed to compare changes or
transitions of state between conditions of interest. The advancements in data intensive …

Disease-modifying therapies and cost-of-illness progression among people newly diagnosed with multiple sclerosis: a national register-based cohort study covering …

K Karampampa, H Gyllensten, E Friberg, C Murley… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Disease-modifying therapies (DMTs) can slow disease progression in multiple
sclerosis (MS). The objective of this study was to explore the cost-of-illness (COI) …

Treatment response score to glatiramer acetate or interferon beta-1a

F Bovis, T Kalincik, F Lublin, G Cutter, C Malpas… - Neurology, 2021 - AAN Enterprises
Objective To compare the effectiveness of glatiramer acetate (GA) vs intramuscular
interferon beta-1a (IFN-β-1a), we applied a previously published statistical method aimed at …