Update on the role of alpha-agonists in glaucoma management

S Arthur, LB Cantor - Experimental Eye Research, 2011 - Elsevier
Glaucoma is the second most common cause of world blindness (following cataract) with
estimated cases reaching 79.6 million by 2020. Although the etiology of glaucoma is multi …

[HTML][HTML] Dorzolamide/timolol fixed combination: learning from the past and looking toward the future

AG Konstas, L Schmetterer, A Katsanos… - Advances in …, 2021 - Springer
The key clinical attributes of preserved dorzolamide/timolol fixed combination (DTFC) and
the emerging potential of preservative-free (PF) DTFC are reviewed with published evidence …

[HTML][HTML] Brimonidine and timolol concentrations in the human vitreous and aqueous humors after topical instillation of a 0.1% brimonidine tartrate and 0.5% timolol …

Y Orii, E Kunikane, Y Yamada, M Morioka, K Iwasaki… - Plos one, 2022 - journals.plos.org
Purpose To evaluate the concentrations of brimonidine and timolol in the vitreous and
aqueous humors after instillation of a 0.1% brimonidine tartrate and 0.5% timolol fixed …

[HTML][HTML] Ocular distribution of brimonidine and brinzolamide after topical instillation of a 0.1% brimonidine tartrate and 1% brinzolamide fixed-combination ophthalmic …

Y Orii, E Kunikane, Y Yamada, M Morioka… - Journal of Clinical …, 2023 - mdpi.com
Purpose: To evaluate the concentrations of brimonidine and brinzolamide in the vitreous
and aqueous humor after instillation of a 0.1% brimonidine tartrate and 1% brinzolamide …

[HTML][HTML] Fixed versus Unfixed Combination of Topical Latanoprost/Timolol for Glaucoma: An Observational Study Investigating the Level of Adherence and Ocular …

V Toumanidou, A Diafas, N Georgiadis… - Journal of Clinical …, 2023 - mdpi.com
Purpose: To investigate the effect of fixed combination versus concomitant unfixed topical
glaucoma treatment on patients' adherence and ocular surface health. Patients and …

[HTML][HTML] Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle …

AGP Konstas, L Quaranta, DB Yan, DG Mikropoulos… - Eye, 2012 - nature.com
Aim The aim of this study is to compare the 24-hour efficacy of dorzolamide/timolol-fixed
combination (DTFC) and brimonidine/timolol-fixed combination (BTFC) in primary open …

[HTML][HTML] Randomized Multicenter Clinical Trial Comparing 0.1% Brimonidine/0.5% Timolol Versus 1% Dorzolamide/0.5% Timolol as Adjuncts to Prostaglandin …

M Inatani, Y Orii, K Iwasaki, S Arimura, H Sunagawa… - Advances in …, 2023 - Springer
Introduction This multicenter, randomized, comparative, and investigator-masked crossover
clinical trial sought to compare the efficacy and tolerability of fixed combinations of 0.1 …

Fixed-combination topical anti-hypertensive ophthalmic agents

L Machen, R Razeghinejad… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Fixed-combination glaucoma medications have altered the paradigm of ocular
hypertension and glaucoma treatment and are in widespread use today. A comprehensive …

Efficacy of the combination of carteolol hydrochloride+ latanoprost in the treatment of glaucoma and ocular hypertension

RR Soares, MR Razeghinejad - Expert opinion on …, 2018 - Taylor & Francis
Introduction: The only evidence-based mechanism for prevention and treatment of
glaucomatous optic neuropathy is decreasing the intraocular pressure (IOP). Prescribing …

Safety, tolerability, and efficacy of fixed combination therapy with dorzolamide hydrochloride 2% and timolol maleate 0.5% in glaucoma and ocular hypertension

NP Bell, JL Ramos, RM Feldman - Clinical Ophthalmology, 2010 - Taylor & Francis
Glaucoma is a collection of diseases characterized by multifactorial progressive changes
leading to visual field loss and optic neuropathy most frequently due to elevated intraocular …