Patterning with clocks and genetic cascades: Segmentation and regionalization of vertebrate versus insect body plans

M Diaz-Cuadros, O Pourquié, E El-Sherif - PLoS Genetics, 2021 - journals.plos.org
Oscillatory and sequential processes have been implicated in the spatial patterning of many
embryonic tissues. For example, molecular clocks delimit segmental boundaries in …

How enhancers regulate wavelike gene expression patterns

C Mau, H Rudolf, F Strobl, B Schmid, T Regensburger… - Elife, 2023 - elifesciences.org
A key problem in development is to understand how genes turn on or off at the right place
and right time during embryogenesis. Such decisions are made by non-coding sequences …

A re-inducible gap gene cascade patterns the anterior–posterior axis of insects in a threshold-free fashion

A Boos, J Distler, H Rudolf, M Klingler, E El-Sherif - Elife, 2018 - elifesciences.org
Gap genes mediate the division of the anterior-posterior axis of insects into different fates
through regulating downstream hox genes. Decades of tinkering the segmentation gene …

[HTML][HTML] Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade

H Rudolf, C Zellner, E El-Sherif - Developmental biology, 2020 - Elsevier
Recently, it was shown that anterior-posterior patterning genes in the red flour beetle
Tribolium castaneum are expressed sequentially in waves. However, in the fruit fly …

How enhancers regulate wavelike gene expression patterns: A novel enhancer prediction and live reporter system identifies an enhancer associated with the arrest of …

C Mau, H Rudolf, F Strobl, B Schmid, T Regensburger… - bioRxiv, 2022 - biorxiv.org
A key problem in development is to understand how genes turn on or off at the right place
and right time during embryogenesis. Such decisions are made by non-coding sequences …

A re-inducible genetic cascade patterns the anterior-posterior axis of insects in a threshold-free fashion

A Boos, J Distler, H Rudolf, M Klingler, E El-Sherif - BioRxiv, 2018 - biorxiv.org
Gap genes mediate the division of the anterior-posterior axis of insects into different fates
through regulating downstream hox genes. Decades of tinkering the segmentation gene …

[图书][B] Biological patterning in networks of interacting cells

ML Perkins - 2020 - search.proquest.com
Biological organisms rely on spatial variation in cell activity to coordinate diverse activities,
such as microbial colonization and embryonic development. Interactions among …