MicroRNA-206 in human cancer: mechanistic and clinical perspectives

LB Khasraghi, M Nouri, M Vazirzadeh, N Hashemipour… - Cellular …, 2023 - Elsevier
Abstract MicroRNAs (miRNAs), small non-coding RNAs approximately 20–25 nt in length,
play important roles via directly binding to the corresponding 3′ UTR of target mRNAs …

The role of the aryl hydrocarbon receptor (AhR) and its ligands in breast cancer

S Safe, L Zhang - Cancers, 2022 - mdpi.com
Simple Summary The aryl hydrocarbon receptor (AhR) is expressed in breast cancer cells
and tumors and in some studies, the AhR is a negative prognostic factor for patient survival …

AhR and cancer: from gene profiling to targeted therapy

A Paris, N Tardif, MD Galibert, S Corre - International journal of molecular …, 2021 - mdpi.com
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that has been
shown to be an essential regulator of a broad spectrum of biological activities required for …

Aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) play both distinct and common roles in the regulation of colon homeostasis and intestinal …

G Vázquez-Gómez, J Petráš, Z Dvořák… - Biochemical …, 2023 - Elsevier
Both aryl hydrocarbon receptor (AhR) and pregnane X receptor (PXR) belong among key
regulators of xenobiotic metabolism in the intestinal tissue. AhR in particular is activated by a …

Aryl hydrocarbon receptor: An emerging player in breast cancer pathogenesis and its potential as a drug target

C Chen, Z Wang, Z Liao, Y Zhang… - Molecular …, 2023 - spandidos-publications.com
Breast cancer is the most common malignancy in women. Metastatic breast cancer is
incurable and is a major cause of shortened patient survival. The different molecular types of …

[HTML][HTML] Emerging roles of MiR-133a in human cancers

YT Hua, WX Xu, H Li, M Xia - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) can post-transcriptionally regulate the expression of cancer-relevant
genes via binding to the 3'-untranslated region (3'-UTR) of the target mRNAs. MiR-133a, as …

[HTML][HTML] Association of high miR-27a, miR-206, and miR-214 expression with poor patient prognosis and increased chemoresistance in triple-negative breast cancer

Y Liu, W Gong, K Panoutsopoulou… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer
subtype, associated with early metastasis and recurrence as well as poor patient outcome …

MicroRNAs: a link between mammary gland development and breast cancer

D Wu, LU Thompson, EM Comelli - International Journal of Molecular …, 2022 - mdpi.com
Breast cancer is among the most common cancers in women, second to skin cancer.
Mammary gland development can influence breast cancer development in later life …

Perspectives on the role of non-coding RNAs in the regulation of expression and function of the estrogen receptor

M Taheri, H Shoorei, ME Dinger, S Ghafouri-Fard - Cancers, 2020 - mdpi.com
Estrogen receptors (ERs) comprise several nuclear and membrane-bound receptors with
different tissue-specific functions. ERα and ERβ are two nuclear members of this family …

MicroRNA-27b-3p promotes tumor progression and metastasis by inhibiting peroxisome proliferator-activated receptor gamma in triple-negative breast cancer

SJ Shen, Y Song, XY Ren, YL Xu, YD Zhou… - Frontiers in …, 2020 - frontiersin.org
Introduction: The role and underlying mechanisms of miR-27b-3p in triple-negative breast
cancer (TNBC) remains unclear. Methods: miR-27b-3p expression level was evaluated in 99 …