Enteric glial cells: a new frontier in neurogastroenterology and clinical target for inflammatory bowel diseases

F Ochoa-Cortes, F Turco, A Linan-Rico… - Inflammatory bowel …, 2016 - academic.oup.com
The word “glia” is derived from the Greek word “γλoια,” glue of the enteric nervous system,
and for many years, enteric glial cells (EGCs) were believed to provide mainly structural …

The enteric glia and its modulation by the endocannabinoid system, a new target for cannabinoid-based nutraceuticals?

L López-Gómez, A Szymaszkiewicz, M Zielińska… - Molecules, 2022 - mdpi.com
The enteric nervous system (ENS) is a part of the autonomic nervous system that intrinsically
innervates the gastrointestinal (GI) tract. Whereas enteric neurons have been deeply …

Molecular signaling and dysfunction of the human reactive enteric glial cell phenotype: implications for GI infection, IBD, POI, neurological, motility, and GI disorders

A Liñán-Rico, F Turco, F Ochoa-Cortes… - Inflammatory bowel …, 2016 - academic.oup.com
Background Clinical observations or animal studies implicate enteric glial cells in motility
disorders, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal (GI) …

BQ788 reveals glial ETB receptor modulation of neuronal cholinergic and nitrergic pathways to inhibit intestinal motility: Linked to postoperative ileus

E Mazzotta, I Grants… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose ET‐1 signalling modulates intestinal motility and inflammation, but
the role of ET‐1/ETB receptor signalling is poorly understood. Enteric glia modulate normal …

Nutraceuticals and enteric glial cells

L López-Gómez, A Szymaszkiewicz, M Zielińska… - Molecules, 2021 - mdpi.com
Until recently, glia were considered to be a structural support for neurons, however further
investigations showed that glial cells are equally as important as neurons. Among many …