Microbial metabolites in colorectal tumorigenesis and cancer therapy

Y Liu, HCH Lau, J Yu - Gut Microbes, 2023 - Taylor & Francis
Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an
ecological community known as the gut microbiota. The gut microbiota is involved in dietary …

[HTML][HTML] Omics technologies for improved diagnosis and treatment of colorectal cancer: Technical advancement and major perspectives

N Dalal, R Jalandra, M Sharma, H Prakash… - Biomedicine & …, 2020 - Elsevier
Colorectal cancer (CRC) ranks third among the most commonly occurring cancers
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …

[HTML][HTML] Methods and biomarkers for early detection, prediction, and diagnosis of colorectal cancer

Y Zhang, Y Wang, B Zhang, P Li, Y Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most common digestive diseases worldwide. It has
steadily ascended to the top three cancers in terms of incidence and mortality. The primary …

[HTML][HTML] Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in …

PHG Sanches, NC de Melo, AM Porcari… - Biology, 2024 - mdpi.com
Simple Summary Recent high-throughput technologies such as transcriptomics, proteomics,
and metabolomics have allowed progress in understanding biological systems at different …

[HTML][HTML] From adenoma to CRC stages: the oral-gut microbiome axis as a source of potential microbial and metabolic biomarkers of malignancy

E Russo, L Di Gloria, G Nannini, G Meoni, E Niccolai… - Neoplasia, 2023 - Elsevier
Abstract Background Approximately 95% of Colorectal cancers (CRC) consist of
adenocarcinomas originating from colonic Adenomatous polyps (AP). Increasing importance …

Urinary charged metabolite profiling of colorectal cancer using capillary electrophoresis-mass spectrometry

R Udo, K Katsumata, H Kuwabara, M Enomoto… - Scientific reports, 2020 - nature.com
Colorectal cancer (CRC) has increasing global prevalence and poor prognostic outcomes,
and the development of low-or less invasive screening tests is urgently required. Urine is an …

Metabolic regulation of prostate cancer heterogeneity and plasticity

C Peitzsch, I Gorodetska, D Klusa, Q Shi… - Seminars in cancer …, 2022 - Elsevier
Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …

Metabolomics profiling discriminates prostate cancer from benign prostatic hyperplasia within the prostate-specific antigen gray zone

B Xu, Y Chen, X Chen, L Gan, Y Zhang, J Feng… - Frontiers in …, 2021 - frontiersin.org
Objective Prostate cancer (PCa) is the second most common male malignancy globally.
Prostate-specific antigen (PSA) is an important biomarker for PCa diagnosis. However, it is …

A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS

N Gray, NG Lawler, R Yang, AC Morillon, MCL Gay… - Talanta, 2021 - Elsevier
Metabolic phenotyping using mass spectrometry (MS) is being applied to ever increasing
sample numbers in clinical and epidemiology studies. High-throughput and robust methods …

UmetaFlow: An untargeted metabolomics workflow for high-throughput data processing and analysis

EE Kontou, A Walter, O Alka, J Pfeuffer… - Journal of …, 2023 - Springer
Metabolomics experiments generate highly complex datasets, which are time and work-
intensive, sometimes even error-prone if inspected manually. Therefore, new methods for …