Microbial metabolites in colorectal tumorigenesis and cancer therapy
Trillions of microbes are indigenous to the human gastrointestinal tract, together forming an
ecological community known as the gut microbiota. The gut microbiota is involved in dietary …
ecological community known as the gut microbiota. The gut microbiota is involved in dietary …
[HTML][HTML] Omics technologies for improved diagnosis and treatment of colorectal cancer: Technical advancement and major perspectives
Colorectal cancer (CRC) ranks third among the most commonly occurring cancers
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …
worldwide, and it causes half a million deaths annually. Alongside mechanistic study for …
[HTML][HTML] Methods and biomarkers for early detection, prediction, and diagnosis of colorectal cancer
Y Zhang, Y Wang, B Zhang, P Li, Y Zhao - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most common digestive diseases worldwide. It has
steadily ascended to the top three cancers in terms of incidence and mortality. The primary …
steadily ascended to the top three cancers in terms of incidence and mortality. The primary …
[HTML][HTML] Integrating Molecular Perspectives: Strategies for Comprehensive Multi-Omics Integrative Data Analysis and Machine Learning Applications in …
PHG Sanches, NC de Melo, AM Porcari… - Biology, 2024 - mdpi.com
Simple Summary Recent high-throughput technologies such as transcriptomics, proteomics,
and metabolomics have allowed progress in understanding biological systems at different …
and metabolomics have allowed progress in understanding biological systems at different …
[HTML][HTML] From adenoma to CRC stages: the oral-gut microbiome axis as a source of potential microbial and metabolic biomarkers of malignancy
Abstract Background Approximately 95% of Colorectal cancers (CRC) consist of
adenocarcinomas originating from colonic Adenomatous polyps (AP). Increasing importance …
adenocarcinomas originating from colonic Adenomatous polyps (AP). Increasing importance …
Urinary charged metabolite profiling of colorectal cancer using capillary electrophoresis-mass spectrometry
R Udo, K Katsumata, H Kuwabara, M Enomoto… - Scientific reports, 2020 - nature.com
Colorectal cancer (CRC) has increasing global prevalence and poor prognostic outcomes,
and the development of low-or less invasive screening tests is urgently required. Urine is an …
and the development of low-or less invasive screening tests is urgently required. Urine is an …
Metabolic regulation of prostate cancer heterogeneity and plasticity
C Peitzsch, I Gorodetska, D Klusa, Q Shi… - Seminars in cancer …, 2022 - Elsevier
Metabolic reprogramming is one of the main hallmarks of cancer cells. It refers to the
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …
metabolic adaptations of tumor cells in response to nutrient deficiency, microenvironmental …
Metabolomics profiling discriminates prostate cancer from benign prostatic hyperplasia within the prostate-specific antigen gray zone
B Xu, Y Chen, X Chen, L Gan, Y Zhang, J Feng… - Frontiers in …, 2021 - frontiersin.org
Objective Prostate cancer (PCa) is the second most common male malignancy globally.
Prostate-specific antigen (PSA) is an important biomarker for PCa diagnosis. However, it is …
Prostate-specific antigen (PSA) is an important biomarker for PCa diagnosis. However, it is …
A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS
Metabolic phenotyping using mass spectrometry (MS) is being applied to ever increasing
sample numbers in clinical and epidemiology studies. High-throughput and robust methods …
sample numbers in clinical and epidemiology studies. High-throughput and robust methods …
UmetaFlow: An untargeted metabolomics workflow for high-throughput data processing and analysis
Metabolomics experiments generate highly complex datasets, which are time and work-
intensive, sometimes even error-prone if inspected manually. Therefore, new methods for …
intensive, sometimes even error-prone if inspected manually. Therefore, new methods for …