Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Abstract Alcohol Use Disorder (AUD) affects around 14.5 million individuals in the United
States, with Substance Use Disorder (SUD) affecting an additional 8.3 million individuals …

Active responses to stressors involve motor planning, execution, and feedback. Here we
identify an insular cortex to BNST (insula→ BNST) circuit recruited during restraint stress …

A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series …

Corticotropin-releasing factor (CRF) in the anterior bed nucleus of the stria terminalis
(aBNST) is associated with chronic stress and avoidance behavior. However, CRF+ BNST …

The sexually dimorphic bed nucleus of the stria terminalis (BNST) is comprised of several
distinct regions, some of which act as a hub for stress-induced changes in neural circuitry …

The prevalence of psychiatry disorders such as anxiety and depression has steadily
increased in recent years in the United States. This increased risk for anxiety and …

Hyperkateifia and stress-induced alcohol cravings drive relapse in individuals with alcohol
use disorder (AUD). The brain stress signal norepinephrine (also known as noradrenaline) …

Alcohol use disorder is a complex psychiatric disorder that can be modeled in rodents using
a number of drinking paradigms. Drinking-in-the-dark (DID) is widely used to model the …

The bed nuclei of the stria terminalis (BST) is a limbic region in the extended amygdala that
is heavily implicated in anxiety processing and hypothalamic-adrenal-pituitary (HPA) axis …