[HTML][HTML] Current understanding of the molecular mechanisms of circulating permeability factor in focal segmental glomerulosclerosis

G Salfi, F Casiraghi, G Remuzzi - Frontiers in immunology, 2023 - frontiersin.org
The pathogenetic mechanisms underlying the onset and the post-transplant recurrence of
primary focal segmental glomerulosclerosis (FSGS) are complex and remain yet to be fully …

[HTML][HTML] KDIGO 2021 clinical practice guideline for the management of glomerular diseases

BH Rovin, SG Adler, J Barratt, F Bridoux… - Kidney …, 2021 - kidney-international.org
Glomerular disease, be it primary or secondary, occurring in the setting of systemic
autoimmune diseases, infections, drugs, or malignancy, affects individuals of all ages. In …

Protecting podocytes: a key target for therapy of focal segmental glomerulosclerosis

KN Campbell, JA Tumlin - American journal of nephrology, 2018 - karger.com
Background: Focal segmental glomerulosclerosis (FSGS) is a histologic pattern of injury
demonstrated by renal biopsy that can arise from a diverse range of causes and …

Tacrolimus combined with corticosteroids versus M odified P onticelli regimen in treatment of idiopathic membranous nephropathy: Randomized control trial

R Ramachandran, HK Hn, V Kumar, R Nada… - …, 2016 - Wiley Online Library
Aim There have been very few studies comparing cyclophosphamide (CTX) and calcineurin
inhibitor based regimens in the management of non‐immunosuppressive symptomatic …

PLA2R antibodies, glomerular PLA2R deposits and variations in PLA2R1 and HLA-DQA1 genes in primary membranous nephropathy in South Asians

R Ramachandran, V Kumar, A Kumar… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Antibodies to M-type phospholipase A2 receptor (PLA2R) correlate with clinical
activity of primary membranous nephropathy (PMN). Risk alleles in PLA2R1 and HLA-DQA1 …

Focal and segmental glomerulosclerosis: clinical and kidney biopsy correlations

S Sethi, L Zand, SH Nasr, RJ Glassock… - Clinical kidney …, 2014 - academic.oup.com
Background Primary focal segmental glomerulosclerosis (FSGS) is a common glomerular
disease in adults and ranks among the top causes of a primary glomerular disease causing …

[HTML][HTML] Mycophenolate mofetil is inferior to tacrolimus in sustaining remission in children with idiopathic steroid-resistant nephrotic syndrome

A Sinha, A Gupta, M Kalaivani, P Hari, AK Dinda… - Kidney International, 2017 - Elsevier
Studies of nephrotic syndrome show that substitution of calcineurin inhibitors by
mycophenolate mofetil (MMF) enables sustained remission and corticosteroid sparing and …

Bioavailable vitamin D levels are reduced and correlate with bone mineral density and markers of mineral metabolism in adults with nephrotic syndrome

A Aggarwal, AK Yadav, R Ramachandran… - …, 2016 - Wiley Online Library
Aim Blood levels of 25‐hydroxyvitamin D [25 (OH) D] are reduced in patients with nephrotic
syndrome (NS). The lowering is thought to be due to urinary loss of vitamin D binding protein …

Treatment strategies of adult primary focal segmental glomerulosclerosis: a systematic review focusing on the last two decades

A Beer, G Mayer, A Kronbichler - BioMed research international, 2016 - Wiley Online Library
Adult primary focal segmental glomerulosclerosis (FSGS) remains a therapeutic challenge
for the treating physician. With the advent of novel immunosuppressive measures, our …

[HTML][HTML] Long-term follow-up of cyclical cyclophosphamide and steroids versus tacrolimus and steroids in primary membranous nephropathy

R Ramachandran, V Kumar, J Bharati, B Rovin… - Kidney International …, 2021 - Elsevier
Introduction Kidney Disease: Improving Global Outcomes (KDIGO) 2012 recommends
cyclical cyclophosphamide plus glucocorticoids (GC)(modified Ponticelli regimen) or …