The last decade has witnessed a high demand of various synthetic approaches towards
bioactive achiral diarylmethanols, diaryl and triarylmethanes and the molecules derived …

The kinesin class of microtubule-associated motor proteins present attractive anticancer
targets owing to their roles in key functions in dividing cells. Two interpolar mitotic kinesins …

Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete
bodies to enable microtubule-mediated transport of one genome copy to each of the newly …

Animal cell shape is largely determined by the cortex, a thin actin network underlying the
plasma membrane in which myosin-driven stresses generate contractile tension. Tension …

Cryo-electron tomography (cryo-ET) allows for label-free high-resolution imaging of
macromolecular assemblies in their native cellular context. However, the localization of …

The life and death of an organism rely on correct cell division, which occurs through the
process of mitosis. Although the biochemical signalling and morphogenetic processes …

Blebs are spherical cellular protrusions that occur in many physiological situations. Two
distinct phases make up the life of a bleb, each of which have their own biology and physics …

Embryonic neocortical development depends on balanced production of progenitors and
neurons. Genetic mutations disrupting progenitor mitosis frequently impair neurogenesis; …

During mitosis, adherent cells round up, by increasing the tension of the contractile
actomyosin cortex while increasing the internal hydrostatic pressure. In the simple scenario …

The cell cortex is a key structure for the regulation of cell shape and tissue organization. To
reach a better understanding of the mechanics and dynamics of the cortex, we study here …