Noncancerous disease-targeting AIEgens

Y Duo, G Luo, W Zhang, R Wang, GG Xiao… - Chemical Society …, 2023 - pubs.rsc.org
Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …

A comprehensive review on peptide-bearing biomaterials: From ex situ to in situ self-assembly

SY Qin, JQ Feng, YJ Cheng, WL Liu, AQ Zhang… - Coordination Chemistry …, 2024 - Elsevier
In the last few decades, we have witnessed the great advances of molecular self-assembly
in biomedical applications. Among the building blocks for molecular self-assembly, peptide …

Multifunctional AIE nanosphere-based “nanobomb” for trimodal imaging-guided photothermal/photodynamic/pharmacological therapy of drug-resistant bacterial …

B Li, W Wang, L Zhao, D Yan, X Li, Q Gao, J Zheng… - ACS …, 2023 - ACS Publications
Injudicious or inappropriate use of antibiotics has led to the prevalence of drug-resistant
bacteria, posing a huge menace to global health. Here, a self-assembled aggregation …

Checkpoint nano‐PROTACs for activatable cancer photo‐immunotherapy

C Zhang, M Xu, S He, J Huang, C Xu… - Advanced Materials, 2023 - Wiley Online Library
Checkpoint immunotherapy holds great potential to treat malignancies via blocking the
immunosuppressive signaling pathways, which however suffers from inefficiency and off …

Diverse interactions between AIEgens and biomolecules/organisms: Advancing from strategic design to precision theranostics

Q Ding, X Xu, Y Li, B Li, Q Saiding, M Gu, W Tao… - Chem, 2024 - cell.com
Fluorophores play a pivotal role in the contemporary biomedical field due to their versatile
interaction with a diverse range of biomolecules and organisms. They are revolutionizing …

Design of Stimuli‐Responsive Peptides and Proteins

Y Li, G Yang, L Gerstweiler, SH Thang… - Advanced Functional …, 2023 - Wiley Online Library
Stimuli‐responsive peptides and proteins are an exciting class of smart biomaterials for
various applications and have received significant attention over the past decades. A wide …

MXene‐Based Aptameric Fluorosensor for Sensitive and Rapid Detection of COVID‐19

Y Luo, X Jiang, R Zhang, C Shen, M Li, Z Zhao, M Lv… - Small, 2023 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐caused COVID‐19
pandemic has rapidly escalated into the largest global health emergency, which pushes to …

Functional materials for subcellular targeting strategies in cancer therapy: progress and prospects

Y Cheng, Z Qu, Q Jiang, T Xu, H Zheng, P Ye… - Advanced …, 2023 - Wiley Online Library
Neoadjuvant and adjuvant therapies have made significant progress in cancer treatment.
However, tumor adjuvant therapy still faces challenges due to the intrinsic heterogeneity of …

Endoproteolysis of oligopeptide-based coacervates for enzymatic modeling

Z Jin, C Ling, W Yim, YC Chang, T He, K Li, J Zhou… - ACS …, 2023 - ACS Publications
Better insights into the fate of membraneless organelles could strengthen the understanding
of the transition from prebiotic components to multicellular organisms. Compartmentalized …

Photostable Cascade‐Activatable Peptide Self‐Assembly on a Cancer Cell Membrane for High‐Performance Identification of Human Bladder Cancer

Z Wang, C Zhao, Y Li, J Wang, D Hou… - Advanced …, 2023 - Wiley Online Library
Missed or residual tumor burden results in high risk for bladder cancer relapse. However,
existing fluorescent probes cannot meet the clinical needs because of inevitable …