[HTML][HTML] Benzimidazole: A Versatile Scaffold for Drug Discovery and Beyond-A Comprehensive Review of Synthetic Approaches and Recent Advancements in …
ND Mahurkar, ND Gawhale, MN Lokhande, SJ Uke… - Results in …, 2023 - Elsevier
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …
Non-Native Site-Selective Enzyme Catalysis
D Mondal, HM Snodgrass, CA Gomez… - Chemical …, 2023 - ACS Publications
The ability to site-selectively modify equivalent functional groups in a molecule has the
potential to streamline syntheses and increase product yields by lowering step counts …
potential to streamline syntheses and increase product yields by lowering step counts …
Metal-organic frameworks (MOFs)-derived ZrOSO4@ C for photocatalytic synthesis of benzimidazole derivatives
Heterocyclic moieties, such as benzimidazole, are examples of important nuclei that have
found widespread use in a variety of scientific subfields, such as medical and applied …
found widespread use in a variety of scientific subfields, such as medical and applied …
Selective Biocatalytic N‐Methylation of Unsaturated Heterocycles
Methods for regioselective N‐methylation and‐alkylation of unsaturated heterocycles with
“off the shelf” reagents are highly sought‐after. This reaction could drastically simplify …
“off the shelf” reagents are highly sought‐after. This reaction could drastically simplify …
Cucurbit[6]uril-Supported Fe3O4 Magnetic Nanoparticles Catalyzed Green and Sustainable Synthesis of 2-Substituted Benzimidazoles via Acceptorless …
A new composite, cucurbit [6] uril (CB [6])-supported magnetic nanoparticles, Fe3O4–CB [6],
was synthesized via a co-precipitation method in air and fully characterized by Fourier …
was synthesized via a co-precipitation method in air and fully characterized by Fourier …
Synthesis, in-vitro α-glucosidase inhibition and molecular docking studies of 1, 3, 4-thiadiazole-5, 6-diphenyl-1, 2, 4-triazine hybrids: potential leads in the search of …
Abstract A series of 1, 3, 4-thiadiazole-5, 6-diphenyl-triazine hybrids 7a-l have been
designed, synthesized and investigated for the α-glucosidase inhibitory activities. All the …
designed, synthesized and investigated for the α-glucosidase inhibitory activities. All the …
Recent achievements in the synthesis of benzimidazole derivatives
NT Chung, VC Dung, DX Duc - RSC advances, 2023 - pubs.rsc.org
Benzimidazoles are a class of heterocyclic compounds in which a benzene ring is fused to
the 4 and 5 positions of an imidazole ring. Benzimidazole refers to the parent compound …
the 4 and 5 positions of an imidazole ring. Benzimidazole refers to the parent compound …
Recent advances in the anticancer applications of benzimidazole derivatives
Cancer, one of the most deadly diseases worldwide, is still a crucial challenge to human
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
well‐being. Hence, the design and development of modern protocols to cure diverse kinds …
Metal-free polychloromethylation/cyclization of unactivated alkenes towards ring-fused tricyclic indolones and benzoimidazoles
Y Wu, H Liu, L Liu, JT Yu - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Polychloromethylative cyclization of N-alkenyl indoles was developed under metal-free
conditions to afford tricyclic pyridoindolones and pyrroloindolones in moderate to good …
conditions to afford tricyclic pyridoindolones and pyrroloindolones in moderate to good …
TiO2/AgSbO3 nanophotocatalyst with improved photocatalytic performance in the synthesis of some benzimidazole derivatives
Due to the fact that TiO 2 semiconductor has a profound surface and a porous structure, this
compound shows a high photocatalytic activity among other similar counterparts. The wide …
compound shows a high photocatalytic activity among other similar counterparts. The wide …