Measuring DNA modifications with the comet assay: a compendium of protocols
A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …
The accelerated aging phenotype: the role of race and social determinants of health on aging
The pursuit to discover the fundamental biology and mechanisms of aging within the context
of the physical and social environment is critical to designing interventions to prevent and …
of the physical and social environment is critical to designing interventions to prevent and …
[HTML][HTML] Worldwide research trends in landslide science
P Carrión-Mero, N Montalván-Burbano… - International journal of …, 2021 - mdpi.com
Landslides are generated by natural causes and by human action, causing various
geomorphological changes as well as physical and socioeconomic loss of the environment …
geomorphological changes as well as physical and socioeconomic loss of the environment …
Using the comet and micronucleus assays for genotoxicity studies: A review
RP Araldi, TC de Melo, TB Mendes… - Biomedicine & …, 2015 - Elsevier
Physical, chemical and biological agents can act in the DNA, resulting in mutation involved
in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate …
in cancer. Thus, genotoxic tests are required by regulatory agencies in order to evaluate …
An overview of comet assay application for detecting DNA damage in aquatic animals
This review discusses several research studies that employed comet assay to evaluate the
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …
environmental impact of genotoxins in aquatic environments. It focuses on in vivo and in situ …
The enzyme-modified comet assay: Past, present and future
D Muruzabal, A Collins, A Azqueta - Food and Chemical Toxicology, 2021 - Elsevier
Highlights•Twelve different enzyme have been used in combination with the comet
assay.•The enzyme-modified comet assay detects several DNA lesions.•Fpg, followed by …
assay.•The enzyme-modified comet assay detects several DNA lesions.•Fpg, followed by …
The comet assay: past, present, and future
SAS Langie, A Azqueta, AR Collins - Frontiers in genetics, 2015 - frontiersin.org
The alkaline comet assay (single cell gel electrophoresis) is the most widely used method
for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks …
for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks …
[HTML][HTML] The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and …
The alkaline comet assay, or single cell gel electrophoresis, is one of the most popular
methods for assessing DNA damage in human population. One of the open issues …
methods for assessing DNA damage in human population. One of the open issues …
The comet assay: ready for 30 more years
P Møller - Mutagenesis, 2018 - academic.oup.com
During the last 30 years, the comet assay has become widely used for the measurement of
DNA damage and repair in cells and tissues. A landmark achievement was reached in 2016 …
DNA damage and repair in cells and tissues. A landmark achievement was reached in 2016 …
The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop
Abstract The International Comet Assay Workshops are a series of scientific conferences
dealing with practical and theoretical aspects of the Comet Assay (single-cell gel …
dealing with practical and theoretical aspects of the Comet Assay (single-cell gel …