Neuroinflammation in primary open-angle glaucoma

S Vernazza, S Tirendi, AM Bassi, CE Traverso… - Journal of clinical …, 2020 - mdpi.com
Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness
worldwide. Increasing evidence suggests oxidative damage and immune response defects …

The application of lncRNAs in cancer treatment and diagnosis

Y Zhang, L Tang - Recent patents on anti-cancer drug …, 2018 - ingentaconnect.com
Background: It is increasingly evident that lncRNAs have various biological functions playing
as essential regulators, getting involved in diverse cellular processes. Many of the lncRNAs …

Melatonin inhibits Müller cell activation and pro‐inflammatory cytokine production via upregulating the MEG3/miR‐204/Sirt1 axis in experimental diabetic retinopathy

Y Tu, M Zhu, Z Wang, K Wang, L Chen… - Journal of cellular …, 2020 - Wiley Online Library
Diabetic retinopathy (DR) is the most common ocular complication caused by diabetes
mellitus and is the main cause of visual impairment in working‐age people. Reactive gliosis …

Epigenetics and signaling pathways in glaucoma

AC Gauthier, J Liu - BioMed research international, 2017 - Wiley Online Library
Glaucoma is the most common cause of irreversible blindness worldwide. This
neurodegenerative disease becomes more prevalent with aging, but predisposing genetic …

Long noncoding RNA KCNQ1OT1 induces pyroptosis in diabetic corneal endothelial keratopathy

Y Zhang, Z Song, X Li, S Xu, S Zhou… - American Journal of …, 2020 - journals.physiology.org
Diabetic corneal endothelial keratopathy is an intractable ocular complication characterized
by corneal edema and endothelial decompensation, which seriously threaten vision. It has …

[PDF][PDF] Circ-ZNF609 promotes carcinogenesis of gastric cancer cells by inhibiting miRNA-145-5p expression.

Z Liu, HM Pan, L Xin, Y Zhang… - European Review for …, 2019 - europeanreview.org
OBJECTIVE: To elucidate the expression pattern and biological function of circular RNA
ZNF609 (circ-ZNF609) in gastric cancer (GC). PATIENTS AND METHODS: Circ-ZNF609 …

Epigenetic regulation of retinal development

R Raeisossadati, MFR Ferrari, AH Kihara, I AlDiri… - Epigenetics & …, 2021 - Springer
In the developing vertebrate retina, retinal progenitor cells (RPCs) proliferate and give rise to
terminally differentiated neurons with exquisite spatio-temporal precision. Lineage …

Global and cell-type specific properties of lincRNAs with ribosome occupancy

H Wang, Y Wang, S Xie, Y Liu, Z Xie - Nucleic acids research, 2017 - academic.oup.com
Advances in transcriptomics have led to the discovery of a large number of long intergenic
non-coding RNAs (lincRNAs), which are now recognized as important regulators of diverse …

Knockdown of NEAT1 exerts suppressive effects on diabetic retinopathy progression via inactivating TGF‐β1 and VEGF signaling pathways

K Shao, L Xi, Z Cang, C Chen… - Journal of Cellular …, 2020 - Wiley Online Library
Diabetic retinopathy (DR) is complication resulted from Type 2 diabetes mellitus.
Accumulating evidence has proved the functions of long noncoding RNAs (lncRNAs) in the …

LncRNA ZNF503-AS1 promotes RPE differentiation by downregulating ZNF503 expression

X Chen, C Jiang, B Qin, G Liu, J Ji, X Sun, M Xu… - Cell death & …, 2017 - nature.com
Long noncoding RNAs (lncRNAs) have important roles in various biological processes. Our
previous work has revealed that dedifferentiation of retinal pigment epithelium (RPE) cells …