Tools for in silico target fishing

A Cereto-Massagué, MJ Ojeda, C Valls, M Mulero… - Methods, 2015 - Elsevier
Computational target fishing methods are designed to identify the most probable target of a
query molecule. This process may allow the prediction of the bioactivity of a compound, the …

Trends in Pharmacognosy: A modern science of natural medicines

N Dhami - Journal of herbal medicine, 2013 - Elsevier
Natural medicines have been used to enhance human and veterinary health since time
immemorial and the success of modern medical science largely depends on drugs originally …

Plant metabolite databases: from herbal medicines to modern drug discovery

TH Nguyen-Vo, L Nguyen, N Do… - Journal of chemical …, 2019 - ACS Publications
Traditional herbal medicine has been an inseparable part of the traditional medical science
in many countries throughout history. Nowadays, the popularity of using herbal medicines in …

Natural products in precision oncology: Plant-based small molecule inhibitors of protein kinases for cancer chemoprevention

HJ Thompson, T Lutsiv - Nutrients, 2023 - mdpi.com
Striking progress is being made in cancer treatment by using small molecule inhibitors of
specific protein kinases that are products of genes recognized as drivers for a specific type …

The potential role of in silico approaches to identify novel bioactive molecules from natural resources

A Olğaç, IE Orhan, E Banoglu - Future Medicinal Chemistry, 2017 - Taylor & Francis
In recent years, integration of in silico approaches to natural product (NP) research
reawakened the declined interest in NP-based drug discovery efforts. In particular …

Antiplasmodial medicinal plants: a literature review on efficacy, selectivity and phytochemistry of crude plant extracts

H Kaur, HM Mukhtar, A Singh… - Journal of Biologically …, 2018 - Taylor & Francis
Global reporting of 5 million more malaria cases in 2016 comparative to 211 million cases
reported in 2015 makes malaria overwhelming parasitic disease caused by Plasmodium …

Использование подходов метаболомики в анализе лекарственных растений и фитопрепаратов (обзор)

АА Орлова, Й Стругар, ОЮ Штарк… - Разработка и …, 2021 - pharmjournal.ru
Аннотация Введение. Целью аналитического обзора является обобщение данных
современной научной литературы о направлениях и возможностях использования …

[HTML][HTML] Advances in computational approaches for drug discovery based on natural products

JL Medina-Franco - Revista latinoamericana de química, 2013 - scielo.org.mx
Drug discovery based on natural products has a long successful history. To further advance
the identification of new drugs from compounds of natural origin, natural product research is …

Zoopharmacology: a way to discover new cancer treatments

EM Domínguez-Martín, J Tavares, P Ríjo… - Biomolecules, 2020 - mdpi.com
Zoopharmacognosy is the multidisciplinary approach of the self-medication behavior of
many kinds of animals. Recent studies showed the presence of antitumoral secondary …

[HTML][HTML] Insights on the molecular mechanism of anti-inflammatory effect of formula from Islamic traditional medicine: An in-silico study

AA Elgazar, HR Knany, MS Ali - Journal of Traditional and Complementary …, 2019 - Elsevier
Background and aim Traditional medicine is an important source for drug discovery.
However, many challenges face the scientific community to develop novel drugs from it. To …